Van Raamsdonk JM - Search Results

1

Cognitive dysfunction precedes neuropathology and motor abnormalities in the YAC128 mouse model of Huntington's disease.

Van Raamsdonk JM, Pearson J, Slow EJ, Hossain SM, Leavitt BR, Hayden MR. Van Raamsdonk JM, et al. J Neurosci. 2005 Apr 20;25(16):4169-80. doi: 10.1523/JNEUROSCI.0590-05.2005. J Neurosci. 2005. PMID: 15843620 Free PMC article.

2

Caspase cleavage of mutant huntingtin precedes neurodegeneration in Huntington's disease.

Wellington CL, Ellerby LM, Gutekunst CA, Rogers D, Warby S, Graham RK, Loubser O, van Raamsdonk J, Singaraja R, Yang YZ, Gafni J, Bredesen D, Hersch SM, Leavitt BR, Roy S, Nicholson DW, Hayden MR. Wellington CL, et al. J Neurosci. 2002 Sep 15;22(18):7862-72. doi: 10.1523/JNEUROSCI.22-18-07862.2002. J Neurosci. 2002. PMID: 12223539 Free PMC article.

3

Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease.

Slow EJ, van Raamsdonk J, Rogers D, Coleman SH, Graham RK, Deng Y, Oh R, Bissada N, Hossain SM, Yang YZ, Li XJ, Simpson EM, Gutekunst CA, Leavitt BR, Hayden MR. Slow EJ, et al. Hum Mol Genet. 2003 Jul 1;12(13):1555-67. doi: 10.1093/hmg/ddg169. Hum Mol Genet. 2003. PMID: 12812983

4

Loss of wild-type huntingtin influences motor dysfunction and survival in the YAC128 mouse model of Huntington disease.

Van Raamsdonk JM, Pearson J, Rogers DA, Bissada N, Vogl AW, Hayden MR, Leavitt BR. Van Raamsdonk JM, et al. Hum Mol Genet. 2005 May 15;14(10):1379-92. doi: 10.1093/hmg/ddi147. Epub 2005 Apr 13. Hum Mol Genet. 2005. PMID: 15829505

5

Treatment of YAC128 mice and their wild-type littermates with cystamine does not lead to its accumulation in plasma or brain: implications for the treatment of Huntington disease.

Pinto JT, Van Raamsdonk JM, Leavitt BR, Hayden MR, Jeitner TM, Thaler HT, Krasnikov BF, Cooper AJ. Pinto JT, et al. Among authors: van raamsdonk jm. J Neurochem. 2005 Aug;94(4):1087-101. doi: 10.1111/j.1471-4159.2005.03255.x. Epub 2005 Jun 30. J Neurochem. 2005. PMID: 15992377 Free article.

6

Ethyl-EPA treatment improves motor dysfunction, but not neurodegeneration in the YAC128 mouse model of Huntington disease.

Van Raamsdonk JM, Pearson J, Rogers DA, Lu G, Barakauskas VE, Barr AM, Honer WG, Hayden MR, Leavitt BR. Van Raamsdonk JM, et al. Exp Neurol. 2005 Dec;196(2):266-72. doi: 10.1016/j.expneurol.2005.07.021. Epub 2005 Aug 29. Exp Neurol. 2005. PMID: 16129433

7

Cystamine treatment is neuroprotective in the YAC128 mouse model of Huntington disease.

Van Raamsdonk JM, Pearson J, Bailey CD, Rogers DA, Johnson GV, Hayden MR, Leavitt BR. Van Raamsdonk JM, et al. J Neurochem. 2005 Oct;95(1):210-20. doi: 10.1111/j.1471-4159.2005.03357.x. J Neurochem. 2005. PMID: 16181425 Free article.

8

Selective degeneration and nuclear localization of mutant huntingtin in the YAC128 mouse model of Huntington disease.

Van Raamsdonk JM, Murphy Z, Slow EJ, Leavitt BR, Hayden MR. Van Raamsdonk JM, et al. Hum Mol Genet. 2005 Dec 15;14(24):3823-35. doi: 10.1093/hmg/ddi407. Epub 2005 Nov 8. Hum Mol Genet. 2005. PMID: 16278236

9

Wild-type huntingtin protects neurons from excitotoxicity.

Leavitt BR, van Raamsdonk JM, Shehadeh J, Fernandes H, Murphy Z, Graham RK, Wellington CL, Raymond LA, Hayden MR. Leavitt BR, et al. Among authors: van raamsdonk jm. J Neurochem. 2006 Feb;96(4):1121-9. doi: 10.1111/j.1471-4159.2005.03605.x. Epub 2006 Jan 17. J Neurochem. 2006. PMID: 16417581 Free article.

10

Body weight is modulated by levels of full-length huntingtin.

Van Raamsdonk JM, Gibson WT, Pearson J, Murphy Z, Lu G, Leavitt BR, Hayden MR. Van Raamsdonk JM, et al. Hum Mol Genet. 2006 May 1;15(9):1513-23. doi: 10.1093/hmg/ddl072. Epub 2006 Mar 28. Hum Mol Genet. 2006. PMID: 16571604

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