The endothelial cell ecto-ADPase responsible for inhibition of platelet function is CD39.
Marcus AJ, Broekman MJ, Drosopoulos JH, Islam N, Alyonycheva TN, Safier LB, Hajjar KA, Posnett DN, Schoenborn MA, Schooley KA, Gayle RB, Maliszewski CR.
Marcus AJ, et al. Among authors: islam n.
J Clin Invest. 1997 Mar 15;99(6):1351-60. doi: 10.1172/JCI119294.
J Clin Invest. 1997.
PMID: 9077545
Free PMC article.
We previously demonstrated that when platelets are in motion and in proximity to endothelial cells, they become unresponsive to agonists (Marcus, A.J., L.B. Safier, K.A. Hajjar, H.L. Ullman, N. Islam, M.J. Broekman, and A.M. Eiroa. 1991. J. Clin. Invest. 88:1690-169 …
We previously demonstrated that when platelets are in motion and in proximity to endothelial cells, they become unresponsive to agonists (Ma …