Hobson JP - Search Results

1

Matriptase-3 is a novel phylogenetically preserved membrane-anchored serine protease with broad serpin reactivity.

Szabo R, Netzel-Arnett S, Hobson JP, Antalis TM, Bugge TH. Szabo R, et al. Among authors: hobson jp. Biochem J. 2005 Aug 15;390(Pt 1):231-42. doi: 10.1042/BJ20050299. Biochem J. 2005. PMID: 15853774 Free PMC article.

2

Potent inhibition and global co-localization implicate the transmembrane Kunitz-type serine protease inhibitor hepatocyte growth factor activator inhibitor-2 in the regulation of epithelial matriptase activity.

Szabo R, Hobson JP, List K, Molinolo A, Lin CY, Bugge TH. Szabo R, et al. Among authors: hobson jp. J Biol Chem. 2008 Oct 24;283(43):29495-504. doi: 10.1074/jbc.M801970200. Epub 2008 Aug 19. J Biol Chem. 2008. PMID: 18713750 Free PMC article.

3

Regulation of cell surface protease matriptase by HAI2 is essential for placental development, neural tube closure and embryonic survival in mice.

Szabo R, Hobson JP, Christoph K, Kosa P, List K, Bugge TH. Szabo R, et al. Among authors: hobson jp. Development. 2009 Aug;136(15):2653-63. doi: 10.1242/dev.038430. Development. 2009. PMID: 19592578 Free PMC article.

4

Mouse DESC1 is located within a cluster of seven DESC1-like genes and encodes a type II transmembrane serine protease that forms serpin inhibitory complexes.

Hobson JP, Netzel-Arnett S, Szabo R, Réhault SM, Church FC, Strickland DK, Lawrence DA, Antalis TM, Bugge TH. Hobson JP, et al. J Biol Chem. 2004 Nov 5;279(45):46981-94. doi: 10.1074/jbc.M403299200. Epub 2004 Aug 24. J Biol Chem. 2004. PMID: 15328353 Free article.

5

Co-localization of the channel activating protease prostasin/(CAP1/PRSS8) with its candidate activator, matriptase.

List K, Hobson JP, Molinolo A, Bugge TH. List K, et al. Among authors: hobson jp. J Cell Physiol. 2007 Oct;213(1):237-45. doi: 10.1002/jcp.21115. J Cell Physiol. 2007. PMID: 17471493

6

Expression and genetic loss of function analysis of the HAT/DESC cluster proteases TMPRSS11A and HAT.

Sales KU, Hobson JP, Wagenaar-Miller R, Szabo R, Rasmussen AL, Bey A, Shah MF, Molinolo AA, Bugge TH. Sales KU, et al. Among authors: hobson jp. PLoS One. 2011;6(8):e23261. doi: 10.1371/journal.pone.0023261. Epub 2011 Aug 10. PLoS One. 2011. PMID: 21853097 Free PMC article.

7

Imaging specific cell-surface proteolytic activity in single living cells.

Hobson JP, Liu S, Rønø B, Leppla SH, Bugge TH. Hobson JP, et al. Nat Methods. 2006 Apr;3(4):259-61. doi: 10.1038/nmeth862. Nat Methods. 2006. PMID: 16554829

8

Imaging specific cell surface protease activity in living cells using reengineered bacterial cytotoxins.

Hobson JP, Liu S, Leppla SH, Bugge TH. Hobson JP, et al. Methods Mol Biol. 2009;539:115-29. doi: 10.1007/978-1-60327-003-8_7. Methods Mol Biol. 2009. PMID: 19377967 Free PMC article.

9

Quantitative high-throughput screening identifies inhibitors of anthrax-induced cell death.

Zhu PJ, Hobson JP, Southall N, Qiu C, Thomas CJ, Lu J, Inglese J, Zheng W, Leppla SH, Bugge TH, Austin CP, Liu S. Zhu PJ, et al. Among authors: hobson jp. Bioorg Med Chem. 2009 Jul 15;17(14):5139-45. doi: 10.1016/j.bmc.2009.05.054. Epub 2009 May 29. Bioorg Med Chem. 2009. PMID: 19540764 Free PMC article.

10

Sphingosine 1-phosphate, present in serum-derived lipoproteins, activates matriptase.

Benaud C, Oberst M, Hobson JP, Spiegel S, Dickson RB, Lin CY. Benaud C, et al. Among authors: hobson jp. J Biol Chem. 2002 Mar 22;277(12):10539-46. doi: 10.1074/jbc.M109064200. Epub 2002 Jan 15. J Biol Chem. 2002. PMID: 11792696 Free article.

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