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IMT504, the prototype of the immunostimulatory oligonucleotides of the PyNTTTTGT class, increases the number of progenitors of mesenchymal stem cells both in vitro and in vivo: potential use in tissue repair therapy.
Hernando Insúa A, Montaner AD, Rodriguez JM, Elías F, Fló J, López RA, Zorzopulos J, Hofer EL, Chasseing NA. Hernando Insúa A, et al. Among authors: lopez ra. Stem Cells. 2007 Apr;25(4):1047-54. doi: 10.1634/stemcells.2006-0479. Stem Cells. 2007. PMID: 17420228
Addition of the immunostimulatory oligonucleotide IMT504 to a seasonal flu vaccine increases hemagglutinin antibody titers in young adult and elder rats, and expands the anti-hemagglutinin antibody repertoire.
Montaner AD, Denichilo A, Rodríguez JM, Fló J, López RA, Pontoriero A, Savy V, Baumeister E, Frank R, Zorzopulos J, Elías F. Montaner AD, et al. Among authors: lopez ra. Nucleic Acid Ther. 2011 Aug;21(4):265-74. doi: 10.1089/nat.2011.0284. Epub 2011 Jul 5. Nucleic Acid Ther. 2011. PMID: 21793787
142 results