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Page 1
Replication fitness and NS5B drug sensitivity of diverse hepatitis C virus isolates characterized by using a transient replication assay.
Ludmerer SW, Graham DJ, Boots E, Murray EM, Simcoe A, Markel EJ, Grobler JA, Flores OA, Olsen DB, Hazuda DJ, LaFemina RL. Ludmerer SW, et al. Among authors: simcoe a. Antimicrob Agents Chemother. 2005 May;49(5):2059-69. doi: 10.1128/AAC.49.5.2059-2069.2005. Antimicrob Agents Chemother. 2005. PMID: 15855532 Free PMC article.
Inhibition of hepatitis C virus RNA replication by 2'-modified nucleoside analogs.
Carroll SS, Tomassini JE, Bosserman M, Getty K, Stahlhut MW, Eldrup AB, Bhat B, Hall D, Simcoe AL, LaFemina R, Rutkowski CA, Wolanski B, Yang Z, Migliaccio G, De Francesco R, Kuo LC, MacCoss M, Olsen DB. Carroll SS, et al. Among authors: simcoe al. J Biol Chem. 2003 Apr 4;278(14):11979-84. doi: 10.1074/jbc.M210914200. Epub 2003 Jan 27. J Biol Chem. 2003. PMID: 12554735 Free article.
Orally bioavailable highly potent HIV protease inhibitors against PI-resistant virus.
Lu Z, Bohn J, Rano T, Rutkowski CA, Simcoe AL, Olsen DB, Schleif WA, Carella A, Gabryelski L, Jin L, Lin JH, Emini E, Chapman K, Tata JR. Lu Z, et al. Among authors: simcoe al. Bioorg Med Chem Lett. 2005 Dec 1;15(23):5311-4. doi: 10.1016/j.bmcl.2005.08.072. Epub 2005 Oct 3. Bioorg Med Chem Lett. 2005. PMID: 16203148