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Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning.
Brigman JL, Wright T, Talani G, Prasad-Mulcare S, Jinde S, Seabold GK, Mathur P, Davis MI, Bock R, Gustin RM, Colbran RJ, Alvarez VA, Nakazawa K, Delpire E, Lovinger DM, Holmes A. Brigman JL, et al. Among authors: lovinger dm. J Neurosci. 2010 Mar 31;30(13):4590-600. doi: 10.1523/JNEUROSCI.0640-10.2010. J Neurosci. 2010. PMID: 20357110 Free PMC article.
A novel substituted aminoquinoline selectively targets voltage-sensitive sodium channel isoforms and NMDA receptor subtypes and alleviates chronic inflammatory and neuropathic pain.
Tabakoff B, Ren W, Vanderlinden L, Snell LD, Matheson CJ, Wang ZJ, Levinson R, Smothers CT, Woodward JJ, Honse Y, Lovinger D, Rush AM, Sather WA, Gustafson DL, Hoffman PL. Tabakoff B, et al. Eur J Pharmacol. 2016 Aug 5;784:1-14. doi: 10.1016/j.ejphar.2016.05.006. Epub 2016 May 5. Eur J Pharmacol. 2016. PMID: 27158117 Free PMC article.
Role of Striatal Direct Pathway 2-Arachidonoylglycerol Signaling in Sociability and Repetitive Behavior.
Shonesy BC, Parrish WP, Haddad HK, Stephenson JR, Báldi R, Bluett RJ, Marks CR, Centanni SW, Folkes OM, Spiess K, Augustin SM, Mackie K, Lovinger DM, Winder DG, Patel S, Colbran RJ. Shonesy BC, et al. Among authors: lovinger dm. Biol Psychiatry. 2018 Aug 15;84(4):304-315. doi: 10.1016/j.biopsych.2017.11.036. Epub 2017 Dec 28. Biol Psychiatry. 2018. PMID: 29458998 Free PMC article.
275 results