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Page 1
Proteasomal degradation of Kir6.2 channel protein and its inhibition by a Na+ channel blocker aprindine.
Tanaka H, Miake J, Notsu T, Sonyama K, Sasaki N, Iitsuka K, Kato M, Taniguchi S, Igawa O, Yoshida A, Shigemasa C, Hoshikawa Y, Kurata Y, Kuniyasu A, Nakayama H, Inagaki N, Nanba E, Shiota G, Morisaki T, Ninomiya H, Kitakaze M, Hisatome I. Tanaka H, et al. Among authors: notsu t. Biochem Biophys Res Commun. 2005 Jun 17;331(4):1001-6. doi: 10.1016/j.bbrc.2005.04.011. Biochem Biophys Res Commun. 2005. PMID: 15882977
Functional stabilization of Kv1.5 protein by Hsp70 in mammalian cell lines.
Hirota Y, Kurata Y, Kato M, Notsu T, Koshida S, Inoue T, Kawata Y, Miake J, Bahrudin U, Li P, Hoshikawa Y, Yamamoto Y, Igawa O, Shirayoshi Y, Nakai A, Ninomiya H, Higaki K, Hiraoka M, Hisatome I. Hirota Y, et al. Among authors: notsu t. Biochem Biophys Res Commun. 2008 Aug 1;372(3):469-74. doi: 10.1016/j.bbrc.2008.05.068. Epub 2008 May 23. Biochem Biophys Res Commun. 2008. PMID: 18502196
Stabilizing effects of eicosapentaenoic acid on Kv1.5 channel protein expressed in mammalian cells.
Koshida S, Kurata Y, Notsu T, Hirota Y, Kuang TY, Li P, Bahrudin U, Harada S, Miake J, Yamamoto Y, Hoshikawa Y, Igawa O, Higaki K, Soma M, Yoshida A, Ninomiya H, Shiota G, Shirayoshi Y, Hisatome I. Koshida S, et al. Among authors: notsu t. Eur J Pharmacol. 2009 Feb 14;604(1-3):93-102. doi: 10.1016/j.ejphar.2008.12.016. Epub 2008 Dec 16. Eur J Pharmacol. 2009. PMID: 19121632
Hsp90 prevents interaction between CHIP and HERG proteins to facilitate maturation of wild-type and mutant HERG proteins.
Iwai C, Li P, Kurata Y, Hoshikawa Y, Morikawa K, Maharani N, Higaki K, Sasano T, Notsu T, Ishido Y, Miake J, Yamamoto Y, Shirayoshi Y, Ninomiya H, Nakai A, Murata S, Yoshida A, Yamamoto K, Hiraoka M, Hisatome I. Iwai C, et al. Among authors: notsu t. Cardiovasc Res. 2013 Dec 1;100(3):520-8. doi: 10.1093/cvr/cvt200. Epub 2013 Aug 20. Cardiovasc Res. 2013. PMID: 23963841
Instability of KCNE1-D85N that causes long QT syndrome: stabilization by verapamil.
Sakata S, Kurata Y, Li P, Notsu T, Morikawa K, Miake J, Higaki K, Yamamoto Y, Yoshida A, Shirayoshi Y, Yamamoto K, Horie M, Ninomiya H, Kanzaki S, Hisatome I. Sakata S, et al. Among authors: notsu t. Pacing Clin Electrophysiol. 2014 Jul;37(7):853-63. doi: 10.1111/pace.12360. Epub 2014 Feb 5. Pacing Clin Electrophysiol. 2014. PMID: 24499369
Stabilization of Kv1.5 channel protein by the inotropic agent olprinone.
Endo R, Kurata Y, Notsu T, Li P, Morikawa K, Kondo T, Ogura K, Miake J, Yoshida A, Shirayoshi Y, Ninomiya H, Higaki K, Kuwabara M, Yamamoto K, Inagaki Y, Hisatome I. Endo R, et al. Among authors: notsu t. Eur J Pharmacol. 2015 Oct 15;765:488-94. doi: 10.1016/j.ejphar.2015.09.013. Epub 2015 Sep 12. Eur J Pharmacol. 2015. PMID: 26368666
Effects of Uric Acid on the NO Production of HUVECs and its Restoration by Urate Lowering Agents.
Mishima M, Hamada T, Maharani N, Ikeda N, Onohara T, Notsu T, Ninomiya H, Miyazaki S, Mizuta E, Sugihara S, Kato M, Ogino K, Kuwabara M, Hirota Y, Yoshida A, Otani N, Anzai N, Hisatome I. Mishima M, et al. Among authors: notsu t. Drug Res (Stuttg). 2016 May;66(5):270-4. doi: 10.1055/s-0035-1569405. Epub 2016 Feb 24. Drug Res (Stuttg). 2016. PMID: 26909689
71 results