Newgard CB - Search Results

1

The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells.

Schisler JC, Jensen PB, Taylor DG, Becker TC, Knop FK, Takekawa S, German M, Weir GC, Lu D, Mirmira RG, Newgard CB. Schisler JC, et al. Among authors: newgard cb. Proc Natl Acad Sci U S A. 2005 May 17;102(20):7297-302. doi: 10.1073/pnas.0502168102. Epub 2005 May 9. Proc Natl Acad Sci U S A. 2005. PMID: 15883383 Free PMC article.

2

Engineering of glucose-stimulated insulin secretion and biosynthesis in non-islet cells.

Hughes SD, Johnson JH, Quaade C, Newgard CB. Hughes SD, et al. Among authors: newgard cb. Proc Natl Acad Sci U S A. 1992 Jan 15;89(2):688-92. doi: 10.1073/pnas.89.2.688. Proc Natl Acad Sci U S A. 1992. PMID: 1309953 Free PMC article.

3

Regulation of beta-cell glucose transporter gene expression.

Chen L, Alam T, Johnson JH, Hughes S, Newgard CB, Unger RH. Chen L, et al. Among authors: newgard cb. Proc Natl Acad Sci U S A. 1990 Jun;87(11):4088-92. doi: 10.1073/pnas.87.11.4088. Proc Natl Acad Sci U S A. 1990. PMID: 2190214 Free PMC article.

4

Adenovirus-mediated overexpression of liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase in gluconeogenic rat hepatoma cells. Paradoxical effect on Fru-2,6-P2 levels.

Argaud D, Lange AJ, Becker TC, Okar DA, el-Maghrabi MR, Newgard CB, Pilkis SJ. Argaud D, et al. Among authors: newgard cb. J Biol Chem. 1995 Oct 13;270(41):24229-36. doi: 10.1074/jbc.270.41.24229. J Biol Chem. 1995. PMID: 7592629 Free article.

5

Overexpression of hexokinase I in isolated islets of Langerhans via recombinant adenovirus. Enhancement of glucose metabolism and insulin secretion at basal but not stimulatory glucose levels.

Becker TC, BeltrandelRio H, Noel RJ, Johnson JH, Newgard CB. Becker TC, et al. Among authors: newgard cb. J Biol Chem. 1994 Aug 19;269(33):21234-8. J Biol Chem. 1994. PMID: 8063745 Free article.

6

GLUT-2 gene transfer into insulinoma cells confers both low and high affinity glucose-stimulated insulin release. Relationship to glucokinase activity.

Ferber S, BeltrandelRio H, Johnson JH, Noel RJ, Cassidy LE, Clark S, Becker TC, Hughes SD, Newgard CB. Ferber S, et al. Among authors: newgard cb. J Biol Chem. 1994 Apr 15;269(15):11523-9. J Biol Chem. 1994. PMID: 8157682 Free article.

7

Differential effects of overexpressed glucokinase and hexokinase I in isolated islets. Evidence for functional segregation of the high and low Km enzymes.

Becker TC, Noel RJ, Johnson JH, Lynch RM, Hirose H, Tokuyama Y, Bell GI, Newgard CB. Becker TC, et al. Among authors: newgard cb. J Biol Chem. 1996 Jan 5;271(1):390-4. doi: 10.1074/jbc.271.1.390. J Biol Chem. 1996. PMID: 8550593 Free article.

8

Regulation of overexpressed hexokinases in liver and islet cells.

Newgard CB, Becker TC, Berman HK, O'Doherty RM. Newgard CB, et al. Biochem Soc Trans. 1997 Feb;25(1):118-22. doi: 10.1042/bst0250118. Biochem Soc Trans. 1997. PMID: 9056855 Review. No abstract available.

9

Overexpression of leptin receptors in pancreatic islets of Zucker diabetic fatty rats restores GLUT-2, glucokinase, and glucose-stimulated insulin secretion.

Wang MY, Koyama K, Shimabukuro M, Mangelsdorf D, Newgard CB, Unger RH. Wang MY, et al. Among authors: newgard cb. Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):11921-6. doi: 10.1073/pnas.95.20.11921. Proc Natl Acad Sci U S A. 1998. PMID: 9751766 Free PMC article.

10

Overexpression of a modified human malonyl-CoA decarboxylase blocks the glucose-induced increase in malonyl-CoA level but has no impact on insulin secretion in INS-1-derived (832/13) beta-cells.

Mulder H, Lu D, Finley J 4th, An J, Cohen J, Antinozzi PA, McGarry JD, Newgard CB. Mulder H, et al. Among authors: newgard cb. J Biol Chem. 2001 Mar 2;276(9):6479-84. doi: 10.1074/jbc.M010364200. Epub 2000 Dec 11. J Biol Chem. 2001. PMID: 11113153 Free article.

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