Gunnarsdottir S - Search Results

1

The human multidrug resistance protein MRP5 transports folates and can mediate cellular resistance against antifolates.

Wielinga P, Hooijberg JH, Gunnarsdottir S, Kathmann I, Reid G, Zelcer N, van der Born K, de Haas M, van der Heijden I, Kaspers G, Wijnholds J, Jansen G, Peters G, Borst P. Wielinga P, et al. Among authors: gunnarsdottir s. Cancer Res. 2005 May 15;65(10):4425-30. doi: 10.1158/0008-5472.CAN-04-2810. Cancer Res. 2005. PMID: 15899835

2

Sensitivity and acquired resistance of BRCA1;p53-deficient mouse mammary tumors to the topoisomerase I inhibitor topotecan.

Zander SA, Kersbergen A, van der Burg E, de Water N, van Tellingen O, Gunnarsdottir S, Jaspers JE, Pajic M, Nygren AO, Jonkers J, Borst P, Rottenberg S. Zander SA, et al. Among authors: gunnarsdottir s. Cancer Res. 2010 Feb 15;70(4):1700-10. doi: 10.1158/0008-5472.CAN-09-3367. Epub 2010 Feb 9. Cancer Res. 2010. PMID: 20145144

3

The glutathione-activated thiopurine prodrugs trans-6-(2-acetylvinylthio)guanine and cis-6-(2-acetylvinylthio)purine cause less in vivo toxicity than 6-thioguanine after single- and multiple-dose regimens.

Gunnarsdottir S, Rucki M, Phillips LA, Young KM, Elfarra AA. Gunnarsdottir S, et al. Mol Cancer Ther. 2002 Nov;1(13):1211-20. Mol Cancer Ther. 2002. PMID: 12479702

4

Novel glutathione-dependent thiopurine prodrugs: evidence for enhanced cytotoxicity in tumor cells and for decreased bone marrow toxicity in mice.

Gunnarsdottir S, Rucki M, Elfarra AA. Gunnarsdottir S, et al. J Pharmacol Exp Ther. 2002 Apr;301(1):77-86. doi: 10.1124/jpet.301.1.77. J Pharmacol Exp Ther. 2002. PMID: 11907160

5

Distinct tissue distribution of metabolites of the novel glutathione-activated thiopurine prodrugs cis-6-(2-acetylvinylthio)purine and trans-6-(2-acetylvinylthio)guanine and 6-thioguanine in the mouse.

Gunnarsdottir S, Elfarra AA. Gunnarsdottir S, et al. Drug Metab Dispos. 2003 Jun;31(6):718-26. doi: 10.1124/dmd.31.6.718. Drug Metab Dispos. 2003. PMID: 12756203

6

Cytotoxicity of the novel glutathione-activated thiopurine prodrugs cis-AVTP [cis-6-(2-acetylvinylthio)purine] and trans-AVTG [trans-6-(2-acetylvinylthio)guanine] results from the National Cancer Institute's anticancer drug screen.

Gunnarsdottir S, Elfarra AA. Gunnarsdottir S, et al. Drug Metab Dispos. 2004 Mar;32(3):321-7. doi: 10.1124/dmd.32.3.321. Drug Metab Dispos. 2004. PMID: 14977866

7

Glutathione-dependent metabolism of cis-3-(9H-purin-6-ylthio)acrylic acid to yield the chemotherapeutic drug 6-mercaptopurine: evidence for two distinct mechanisms in rats.

Gunnarsdottir S, Elfarra AA. Gunnarsdottir S, et al. J Pharmacol Exp Ther. 1999 Sep;290(3):950-7. J Pharmacol Exp Ther. 1999. PMID: 10454464

8

Human glutathione transferases catalyzing the bioactivation of anticancer thiopurine prodrugs.

Eklund BI, Gunnarsdottir S, Elfarra AA, Mannervik B. Eklund BI, et al. Among authors: gunnarsdottir s. Biochem Pharmacol. 2007 Jun 1;73(11):1829-41. doi: 10.1016/j.bcp.2007.02.002. Epub 2007 Feb 12. Biochem Pharmacol. 2007. PMID: 17433263

9

[Prediction of cancer incidence and prevalence in Iceland up to the year 2040 - Icelandic Cancer Registry and Research Center].

Gudmundsdottir EM, Olafsdottir E, Kristinsdottir NM, Haraldsdottir A, Sigurdardottir K, Tryggvadottir L, Birgisson H, Gunnarsdottir S. Gudmundsdottir EM, et al. Among authors: gunnarsdottir s. Laeknabladid. 2024 Jul;110(7):354-359. doi: 10.17992/lbl.2024.0708.800. Laeknabladid. 2024. PMID: 38934717 Free article. Icelandic.

10

[Cancer registration in Iceland for 70 years - incidence, mortality and survival].

Haraldsdottir A, Birgisson H, Olafsdottir EJ, Gunnarsdottir S, Tryggvadottir L. Haraldsdottir A, et al. Among authors: gunnarsdottir s. Laeknabladid. 2024 Jun;110(6):307-314. doi: 10.17992/lbl.2024.06.797. Laeknabladid. 2024. PMID: 38809221 Free article. Icelandic.

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