Keith KA - Search Results

1

The 4',4'-difluoro analog of 5'-noraristeromycin: a new structural prototype for possible antiviral drug development toward orthopoxvirus and cytomegalovirus.

Roy A, Schneller SW, Keith KA, Hartline CB, Kern ER. Roy A, et al. Among authors: keith ka. Bioorg Med Chem. 2005 Jul 15;13(14):4443-9. doi: 10.1016/j.bmc.2005.04.044. Bioorg Med Chem. 2005. PMID: 15908221

2

Enhanced inhibition of orthopoxvirus replication in vitro by alkoxyalkyl esters of cidofovir and cyclic cidofovir.

Kern ER, Hartline C, Harden E, Keith K, Rodriguez N, Beadle JR, Hostetler KY. Kern ER, et al. Antimicrob Agents Chemother. 2002 Apr;46(4):991-5. doi: 10.1128/AAC.46.4.991-995.2002. Antimicrob Agents Chemother. 2002. PMID: 11897580 Free PMC article.

3

Evaluation of nucleoside phosphonates and their analogs and prodrugs for inhibition of orthopoxvirus replication.

Keith KA, Hitchcock MJ, Lee WA, Holý A, Kern ER. Keith KA, et al. Antimicrob Agents Chemother. 2003 Jul;47(7):2193-8. doi: 10.1128/AAC.47.7.2193-2198.2003. Antimicrob Agents Chemother. 2003. PMID: 12821467 Free PMC article.

4

Inhibitory activity of alkoxyalkyl and alkyl esters of cidofovir and cyclic cidofovir against orthopoxvirus replication in vitro.

Keith KA, Wan WB, Ciesla SL, Beadle JR, Hostetler KY, Kern ER. Keith KA, et al. Antimicrob Agents Chemother. 2004 May;48(5):1869-71. doi: 10.1128/AAC.48.5.1869-1871.2004. Antimicrob Agents Chemother. 2004. PMID: 15105146 Free PMC article.

5

Combinatorial optimization of isatin-beta-thiosemicarbazones as anti-poxvirus agents.

Pirrung MC, Pansare SV, Sarma KD, Keith KA, Kern ER. Pirrung MC, et al. Among authors: keith ka. J Med Chem. 2005 Apr 21;48(8):3045-50. doi: 10.1021/jm049147h. J Med Chem. 2005. PMID: 15828843

6

Distinct thymidine kinases encoded by cowpox virus and herpes simplex virus contribute significantly to the differential antiviral activity of nucleoside analogs.

Prichard MN, Williams AD, Keith KA, Harden EA, Kern ER. Prichard MN, et al. Among authors: keith ka. Antiviral Res. 2006 Aug;71(1):1-6. doi: 10.1016/j.antiviral.2006.01.013. Epub 2006 Feb 28. Antiviral Res. 2006. PMID: 16530858

7

Synthesis and antiviral evaluation of alkoxyalkyl derivatives of 9-(S)-(3-hydroxy-2-phosphonomethoxypropyl)adenine against cytomegalovirus and orthopoxviruses.

Beadle JR, Wan WB, Ciesla SL, Keith KA, Hartline C, Kern ER, Hostetler KY. Beadle JR, et al. Among authors: keith ka. J Med Chem. 2006 Mar 23;49(6):2010-5. doi: 10.1021/jm050473m. J Med Chem. 2006. PMID: 16539388

8

Activity and mechanism of action of N-methanocarbathymidine against herpesvirus and orthopoxvirus infections.

Prichard MN, Keith KA, Quenelle DC, Kern ER. Prichard MN, et al. Among authors: keith ka. Antimicrob Agents Chemother. 2006 Apr;50(4):1336-41. doi: 10.1128/AAC.50.4.1336-1341.2006. Antimicrob Agents Chemother. 2006. PMID: 16569849 Free PMC article.

9

A pyrimidine-pyrazolone nucleoside chimera with potent in vitro anti-orthopoxvirus activity.

Fan X, Zhang X, Zhou L, Keith KA, Kern ER, Torrence PF. Fan X, et al. Among authors: keith ka. Bioorg Med Chem Lett. 2006 Jun 15;16(12):3224-8. doi: 10.1016/j.bmcl.2006.03.043. Epub 2006 Apr 5. Bioorg Med Chem Lett. 2006. PMID: 16603351

10

In vitro and in vivo evaluation of isatin-beta-thiosemicarbazone and marboran against vaccinia and cowpox virus infections.

Quenelle DC, Keith KA, Kern ER. Quenelle DC, et al. Among authors: keith ka. Antiviral Res. 2006 Aug;71(1):24-30. doi: 10.1016/j.antiviral.2006.02.010. Epub 2006 Mar 29. Antiviral Res. 2006. PMID: 16621041

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