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CTLA-4 expressed by chemoresistant, as well as untreated, myeloid leukaemia cells can be targeted with ligands to induce apoptosis.
Laurent S, Palmisano GL, Martelli AM, Kato T, Tazzari PL, Pierri I, Clavio M, Dozin B, Balbi G, Megna M, Morabito A, Lamparelli T, Bacigalupo A, Gobbi M, Pistillo MP. Laurent S, et al. Among authors: kato t. Br J Haematol. 2007 Feb;136(4):597-608. doi: 10.1111/j.1365-2141.2006.06472.x. Br J Haematol. 2007. PMID: 17367412 Free article.
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