McMahon M - Search Results

1

Conditional EGFR promotes cell cycle progression and prevention of apoptosis in the absence of autocrine cytokines.

Shelton JG, Steelman LS, Abrams SL, White ER, Akula SM, Franklin RA, Bertrand FE, McMahon M, McCubrey JA. Shelton JG, et al. Among authors: mcmahon m. Cell Cycle. 2005 Jun;4(6):822-30. doi: 10.4161/cc.4.6.1724. Epub 2005 Jun 7. Cell Cycle. 2005. PMID: 15917660

2

Differential abilities of activated Raf oncoproteins to abrogate cytokine dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells.

McCubrey JA, Steelman LS, Hoyle PE, Blalock WL, Weinstein-Oppenheimer C, Franklin RA, Cherwinski H, Bosch E, McMahon M. McCubrey JA, et al. Among authors: mcmahon m. Leukemia. 1998 Dec;12(12):1903-29. doi: 10.1038/sj.leu.2401215. Leukemia. 1998. PMID: 9844921

3

A conditionally-active form of MEK1 results in autocrine tranformation of human and mouse hematopoietic cells.

Blalock WL, Pearce M, Steelman LS, Franklin RA, McCarthy SA, Cherwinski H, McMahon M, McCubrey JA. Blalock WL, et al. Among authors: mcmahon m. Oncogene. 2000 Jan 27;19(4):526-36. doi: 10.1038/sj.onc.1203337. Oncogene. 2000. PMID: 10698522

4

Differential abilities of the Raf family of protein kinases to abrogate cytokine dependency and prevent apoptosis in murine hematopoietic cells by a MEK1-dependent mechanism.

Hoyle PE, Moye PW, Steelman LS, Blalock WL, Franklin RA, Pearce M, Cherwinski H, Bosch E, McMahon M, McCubrey JA. Hoyle PE, et al. Among authors: mcmahon m. Leukemia. 2000 Apr;14(4):642-56. doi: 10.1038/sj.leu.2401720. Leukemia. 2000. PMID: 10764150

5

Synergy between Raf and BCL2 in abrogating the cytokine dependency of hematopoietic cells.

Moye PW, Blalock WL, Hoyle PE, Chang F, Franklin RA, Weinstein-Oppenheimer C, Pearce M, Steelman L, McMahon M, McCubrey JA. Moye PW, et al. Among authors: mcmahon m. Leukemia. 2000 Jun;14(6):1060-79. doi: 10.1038/sj.leu.2401792. Leukemia. 2000. PMID: 10865973

6

Combined effects of aberrant MEK1 activity and BCL2 overexpression on relieving the cytokine dependency of human and murine hematopoietic cells.

Blalock WL, Moye PW, Chang F, Pearce M, Steelman LS, McMahon M, McCubrey JA. Blalock WL, et al. Among authors: mcmahon m. Leukemia. 2000 Jun;14(6):1080-96. doi: 10.1038/sj.leu.2401793. Leukemia. 2000. PMID: 10865974

7

Effects of inducible MEK1 activation on the cytokine dependency of lymphoid cells.

Blalock WL, Pearce M, Chang F, Lee JT, Pohnert SC, Burrows C, Steelman LS, Franklin RA, McMahon M, McCubrey JA. Blalock WL, et al. Among authors: mcmahon m. Leukemia. 2001 May;15(5):794-807. doi: 10.1038/sj.leu.2402109. Leukemia. 2001. PMID: 11368441

8

Role of the Raf signal transduction cascade in the in vitro resistance to the anticancer drug doxorubicin.

Weinstein-Oppenheimer CR, Henríquez-Roldán CF, Davis JM, Navolanic PM, Saleh OA, Steelman LS, Franklin RA, Robinson PJ, McMahon M, McCubrey JA. Weinstein-Oppenheimer CR, et al. Among authors: mcmahon m. Clin Cancer Res. 2001 Sep;7(9):2898-907. Clin Cancer Res. 2001. PMID: 11555608

9

Effects of the RAF/MEK/ERK and PI3K/AKT signal transduction pathways on the abrogation of cytokine-dependence and prevention of apoptosis in hematopoietic cells.

Shelton JG, Steelman LS, Lee JT, Knapp SL, Blalock WL, Moye PW, Franklin RA, Pohnert SC, Mirza AM, McMahon M, McCubrey JA. Shelton JG, et al. Among authors: mcmahon m. Oncogene. 2003 Apr 24;22(16):2478-92. doi: 10.1038/sj.onc.1206321. Oncogene. 2003. PMID: 12717425

10

Requirement for the PI3K/Akt pathway in MEK1-mediated growth and prevention of apoptosis: identification of an Achilles heel in leukemia.

Blalock WL, Navolanic PM, Steelman LS, Shelton JG, Moye PW, Lee JT, Franklin RA, Mirza A, McMahon M, White MK, McCubrey JA. Blalock WL, et al. Among authors: mcmahon m. Leukemia. 2003 Jun;17(6):1058-67. doi: 10.1038/sj.leu.2402925. Leukemia. 2003. PMID: 12764369

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