Cacho M - Search Results

1

Adrenomedullin: a new target for the design of small molecule modulators with promising pharmacological activities.

Julián M, Cacho M, García MA, Martín-Santamaría S, de Pascual-Teresa B, Ramos A, Martínez A, Cuttitta F. Julián M, et al. Among authors: cacho m. Eur J Med Chem. 2005 Aug;40(8):737-50. doi: 10.1016/j.ejmech.2004.10.016. Eur J Med Chem. 2005. PMID: 15927308 Review.

2

Synthesis, biological evaluation, and three-dimensional quantitative structure-activity relationship study of small-molecule positive modulators of adrenomedullin.

García MA, Martín-Santamaría S, Cacho M, de la Llave FM, Julián M, Martínez A, de Pascual-Teresa B, Ramos A. García MA, et al. Among authors: cacho m. J Med Chem. 2005 Jun 16;48(12):4068-75. doi: 10.1021/jm050021+. J Med Chem. 2005. PMID: 15943480

3

Synthesis, antitumor activity, molecular modeling, and DNA binding properties of a new series of imidazonaphthalimides.

Braña MF, Cacho M, García MA, de Pascual-Teresa B, Ramos A, Acero N, Llinares F, Muñoz-Mingarro D, Abradelo C, Rey-Stolle MF, Yuste M. Braña MF, et al. Among authors: cacho m. J Med Chem. 2002 Dec 19;45(26):5813-6. doi: 10.1021/jm020950q. J Med Chem. 2002. PMID: 12477366

4

New analogues of amonafide and elinafide, containing aromatic heterocycles: synthesis, antitumor activity, molecular modeling, and DNA binding properties.

Braña MF, Cacho M, García MA, de Pascual-Teresa B, Ramos A, Domínguez MT, Pozuelo JM, Abradelo C, Rey-Stolle MF, Yuste M, Báñez-Coronel M, Lacal JC. Braña MF, et al. Among authors: cacho m. J Med Chem. 2004 Mar 11;47(6):1391-9. doi: 10.1021/jm0308850. J Med Chem. 2004. PMID: 14998328

5

Pyrazolo[3,4-c]pyridazines as novel and selective inhibitors of cyclin-dependent kinases.

Braña MF, Cacho M, García ML, Mayoral EP, López B, de Pascual-Teresa B, Ramos A, Acero N, Llinares F, Muñoz-Mingarro D, Lozach O, Meijer L. Braña MF, et al. Among authors: cacho m. J Med Chem. 2005 Nov 3;48(22):6843-54. doi: 10.1021/jm058013g. J Med Chem. 2005. PMID: 16250643

6

Intercalators as anticancer drugs.

Braña MF, Cacho M, Gradillas A, de Pascual-Teresa B, Ramos A. Braña MF, et al. Among authors: cacho m. Curr Pharm Des. 2001 Nov;7(17):1745-80. doi: 10.2174/1381612013397113. Curr Pharm Des. 2001. PMID: 11562309 Review.

7

Synthesis, biological evaluation and DNA binding properties of novel mono and bisnaphthalimides.

Braña MF, Cacho M, Ramos A, Domínguez MT, Pozuelo JM, Abradelo C, Rey-Stolle MF, Yuste M, Carrasco C, Bailly C. Braña MF, et al. Among authors: cacho m. Org Biomol Chem. 2003 Feb 21;1(4):648-54. doi: 10.1039/b209042b. Org Biomol Chem. 2003. PMID: 12929451

8

Chromophore-modified bisnaphthalimides: DNA recognition, topoisomerase inhibition, and cytotoxic properties of two mono- and bisfuronaphthalimides.

Bailly C, Carrasco C, Joubert A, Bal C, Wattez N, Hildebrand MP, Lansiaux A, Colson P, Houssier C, Cacho M, Ramos A, Braña MF. Bailly C, et al. Among authors: cacho m. Biochemistry. 2003 Apr 15;42(14):4136-50. doi: 10.1021/bi027415c. Biochemistry. 2003. PMID: 12680768

9

Optimization of Hydantoins as Potent Antimycobacterial Decaprenylphosphoryl-β-d-Ribose Oxidase (DprE1) Inhibitors.

Balabon O, Pitta E, Rogacki MK, Meiler E, Casanueva R, Guijarro L, Huss S, Lopez-Roman EM, Santos-Villarejo Á, Augustyns K, Ballell L, Aguirre DB, Bates RH, Cunningham F, Cacho M, Van der Veken P. Balabon O, et al. Among authors: cacho m. J Med Chem. 2020 May 28;63(10):5367-5386. doi: 10.1021/acs.jmedchem.0c00107. Epub 2020 May 13. J Med Chem. 2020. PMID: 32342688

10

Mycobacterium tuberculosis Decaprenylphosphoryl-β-d-ribose Oxidase Inhibitors: Expeditious Reconstruction of Suboptimal Hits into a Series with Potent in Vivo Activity.

Borthwick JA, Alemparte C, Wall I, Whitehurst BC, Argyrou A, Burley G, de Dios-Anton P, Guijarro L, Monteiro MC, Ortega F, Suckling CJ, Pichel JC, Cacho M, Young RJ. Borthwick JA, et al. Among authors: cacho m. J Med Chem. 2020 Mar 12;63(5):2557-2576. doi: 10.1021/acs.jmedchem.9b01561. Epub 2020 Jan 22. J Med Chem. 2020. PMID: 31922409 Free article.

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