Edelmann W - Search Results

1

Mutation in Rpa1 results in defective DNA double-strand break repair, chromosomal instability and cancer in mice.

Wang Y, Putnam CD, Kane MF, Zhang W, Edelmann L, Russell R, Carrión DV, Chin L, Kucherlapati R, Kolodner RD, Edelmann W. Wang Y, et al. Among authors: edelmann l, edelmann w. Nat Genet. 2005 Jul;37(7):750-5. doi: 10.1038/ng1587. Epub 2005 Jun 19. Nat Genet. 2005. PMID: 15965476

2

Dominant effects of an Msh6 missense mutation on DNA repair and cancer susceptibility.

Yang G, Scherer SJ, Shell SS, Yang K, Kim M, Lipkin M, Kucherlapati R, Kolodner RD, Edelmann W. Yang G, et al. Among authors: edelmann w. Cancer Cell. 2004 Aug;6(2):139-50. doi: 10.1016/j.ccr.2004.06.024. Cancer Cell. 2004. PMID: 15324697 Free article.

3

Cis lethal genetic interactions attenuate and alter p53 tumorigenesis.

Wang Y, Zhang W, Edelmann L, Kolodner RD, Kucherlapati R, Edelmann W. Wang Y, et al. Among authors: edelmann l, edelmann w. Proc Natl Acad Sci U S A. 2010 Mar 23;107(12):5511-5. doi: 10.1073/pnas.1001223107. Epub 2010 Mar 8. Proc Natl Acad Sci U S A. 2010. PMID: 20212136 Free PMC article.

4

Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility.

Wei K, Clark AB, Wong E, Kane MF, Mazur DJ, Parris T, Kolas NK, Russell R, Hou H Jr, Kneitz B, Yang G, Kunkel TA, Kolodner RD, Cohen PE, Edelmann W. Wei K, et al. Among authors: edelmann w. Genes Dev. 2003 Mar 1;17(5):603-14. doi: 10.1101/gad.1060603. Genes Dev. 2003. PMID: 12629043 Free PMC article.

5

An Msh2 point mutation uncouples DNA mismatch repair and apoptosis.

Lin DP, Wang Y, Scherer SJ, Clark AB, Yang K, Avdievich E, Jin B, Werling U, Parris T, Kurihara N, Umar A, Kucherlapati R, Lipkin M, Kunkel TA, Edelmann W. Lin DP, et al. Among authors: edelmann w. Cancer Res. 2004 Jan 15;64(2):517-22. doi: 10.1158/0008-5472.can-03-2957. Cancer Res. 2004. PMID: 14744764

6

Mouse models for human DNA mismatch-repair gene defects.

Wei K, Kucherlapati R, Edelmann W. Wei K, et al. Among authors: edelmann w. Trends Mol Med. 2002 Jul;8(7):346-53. doi: 10.1016/s1471-4914(02)02359-6. Trends Mol Med. 2002. PMID: 12114115 Review.

7

Loss of DNA mismatch repair function and cancer predisposition in the mouse: animal models for human hereditary nonpolyposis colorectal cancer.

Edelmann L, Edelmann W. Edelmann L, et al. Among authors: edelmann w. Am J Med Genet C Semin Med Genet. 2004 Aug 15;129C(1):91-9. doi: 10.1002/ajmg.c.30021. Am J Med Genet C Semin Med Genet. 2004. PMID: 15264277 Review.

8

Mutation in the mismatch repair gene Msh6 causes cancer susceptibility.

Edelmann W, Yang K, Umar A, Heyer J, Lau K, Fan K, Liedtke W, Cohen PE, Kane MF, Lipford JR, Yu N, Crouse GF, Pollard JW, Kunkel T, Lipkin M, Kolodner R, Kucherlapati R. Edelmann W, et al. Cell. 1997 Nov 14;91(4):467-77. doi: 10.1016/s0092-8674(00)80433-x. Cell. 1997. PMID: 9390556 Free article.

9

Mammalian MutS homologue 5 is required for chromosome pairing in meiosis.

Edelmann W, Cohen PE, Kneitz B, Winand N, Lia M, Heyer J, Kolodner R, Pollard JW, Kucherlapati R. Edelmann W, et al. Nat Genet. 1999 Jan;21(1):123-7. doi: 10.1038/5075. Nat Genet. 1999. PMID: 9916805

10

The DNA mismatch repair genes Msh3 and Msh6 cooperate in intestinal tumor suppression.

Edelmann W, Umar A, Yang K, Heyer J, Kucherlapati M, Lia M, Kneitz B, Avdievich E, Fan K, Wong E, Crouse G, Kunkel T, Lipkin M, Kolodner RD, Kucherlapati R. Edelmann W, et al. Cancer Res. 2000 Feb 15;60(4):803-7. Cancer Res. 2000. PMID: 10706084

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