Brunner J - Search Results

1

Metabolism and disposition of a potent group II metabotropic glutamate receptor agonist, in rats, dogs, and monkeys.

James JK, Nakamura M, Nakazato A, Zhang KE, Cramer M, Brunner J, Cook J, Chen WG. James JK, et al. Among authors: brunner j. Drug Metab Dispos. 2005 Sep;33(9):1373-81. doi: 10.1124/dmd.105.004978. Epub 2005 Jun 24. Drug Metab Dispos. 2005. PMID: 15980102

2

Induction of CYP1A in the beagle dog by an inhibitor of kinase insert domain-containing receptor: differential effects in vitro and in vivo on mRNA and functional activity.

Gibson CR, Lin C, Singh R, Brown CM, Richards K, Brunner J, Michel K, Adelsberger J, Carlini E, Boothe-Genthe C, Raab C, Luu M, Michael A, Parikh M, Ciecko P, Subramanian R, Krolikowski P, Rodrigues AD, Baillie TA, Rushmore TH. Gibson CR, et al. Among authors: brunner j. Drug Metab Dispos. 2005 Jul;33(7):1044-51. doi: 10.1124/dmd.105.003913. Epub 2005 Apr 15. Drug Metab Dispos. 2005. PMID: 15833927

3

Evaluation of microdosing strategies for studies in preclinical drug development: demonstration of linear pharmacokinetics in dogs of a nucleoside analog over a 50-fold dose range.

Sandhu P, Vogel JS, Rose MJ, Ubick EA, Brunner JE, Wallace MA, Adelsberger JK, Baker MP, Henderson PT, Pearson PG, Baillie TA. Sandhu P, et al. Among authors: brunner je. Drug Metab Dispos. 2004 Nov;32(11):1254-9. doi: 10.1124/dmd.104.000422. Epub 2004 Jul 30. Drug Metab Dispos. 2004. PMID: 15286054

4

Differences in the metabolism and pharmacokinetics of two structurally similar PPAR agonists in dogs: involvement of taurine conjugation.

Kim MS, Shen Z, Kochansky C, Lynn K, Wang S, Wang Z, Hora D, Brunner J, Franklin RB, Vincent SH. Kim MS, et al. Among authors: brunner j. Xenobiotica. 2004 Jul;34(7):665-74. doi: 10.1080/00498250412331285445. Xenobiotica. 2004. PMID: 15672754

5

Interconversion pharmacokinetics of simvastatin and its hydroxy acid in dogs: effects of gemfibrozil.

Prueksaritanont T, Qiu Y, Mu L, Michel K, Brunner J, Richards KM, Lin JH. Prueksaritanont T, et al. Among authors: brunner j. Pharm Res. 2005 Jul;22(7):1101-9. doi: 10.1007/s11095-005-6037-2. Epub 2005 Jul 22. Pharm Res. 2005. PMID: 16028010

6

Population pharmacokinetic modeling for enterohepatic recirculation in Rhesus monkey.

Shou M, Lu W, Kari PH, Xiang C, Liang Y, Lu P, Cui D, Emary WB, Michel KB, Adelsberger JK, Brunner JE, Rodrigues AD. Shou M, et al. Eur J Pharm Sci. 2005 Oct;26(2):151-61. doi: 10.1016/j.ejps.2005.05.010. Eur J Pharm Sci. 2005. PMID: 16085400

7

An in vivo microdialysis coupled with liquid chromatography/tandem mass spectrometry study of cortisol metabolism in monkey adipose tissue.

Sun L, Stenken JA, Brunner JE, Michel KB, Adelsberger JK, Yang AY, Zhao JJ, Musson DG. Sun L, et al. Among authors: brunner je. Anal Biochem. 2008 Oct 15;381(2):214-23. doi: 10.1016/j.ab.2008.06.036. Epub 2008 Jul 2. Anal Biochem. 2008. PMID: 18638442

8

Simultaneous determination of urinary free cortisol and 6beta-hydroxycortisol by liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry and its application for estimating hepatic CYP3A induction.

Tang C, Kassahun K, McIntosh IS, Brunner J, Rodrigues AD. Tang C, et al. Among authors: brunner j. J Chromatogr B Biomed Sci Appl. 2000 Jun 9;742(2):303-13. doi: 10.1016/s0378-4347(00)00175-4. J Chromatogr B Biomed Sci Appl. 2000. PMID: 10901135

9

The use of stable isotope labeling and liquid chromatography-tandem mass spectrometry techniques to simultaneously determine the oral and ophthalmic bioavailability of timolol in dogs.

Gilbert JD, Olah TV, Morris MJ, Bortnick A, Brunner J. Gilbert JD, et al. Among authors: brunner j. J Chromatogr Sci. 1998 Apr;36(4):163-8. doi: 10.1093/chromsci/36.3.163. J Chromatogr Sci. 1998. PMID: 9563202

10

Automated molecular weight assignment of electrospray ionization mass spectra.

Williams JD, Weiner BE, Ormand JR, Brunner J, Thornquest AD Jr, Burinsky DJ. Williams JD, et al. Among authors: brunner j. Rapid Commun Mass Spectrom. 2001;15(24):2446-55. doi: 10.1002/rcm.519. Rapid Commun Mass Spectrom. 2001. PMID: 11746916

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