Taylor D - Search Results

1

Reversal of chloroquine resistance in Plasmodium falciparum by 9H-xanthene derivatives.

Wu CP, van Schalkwyk DA, Taylor D, Smith PJ, Chibale K. Wu CP, et al. Among authors: taylor d. Int J Antimicrob Agents. 2005 Aug;26(2):170-5. doi: 10.1016/j.ijantimicag.2005.04.018. Int J Antimicrob Agents. 2005. PMID: 16009536

2

Role of the neurotransmitter reuptake-blocking activity of antidepressants in reversing chloroquine resistance in vitro in Plasmodium falciparum.

Taylor D, Walden JC, Robins AH, Smith PJ. Taylor D, et al. Antimicrob Agents Chemother. 2000 Oct;44(10):2689-92. doi: 10.1128/AAC.44.10.2689-2692.2000. Antimicrob Agents Chemother. 2000. PMID: 10991845 Free PMC article.

3

Fate of haem iron in the malaria parasite Plasmodium falciparum.

Egan TJ, Combrinck JM, Egan J, Hearne GR, Marques HM, Ntenteni S, Sewell BT, Smith PJ, Taylor D, van Schalkwyk DA, Walden JC. Egan TJ, et al. Among authors: taylor d. Biochem J. 2002 Jul 15;365(Pt 2):343-7. doi: 10.1042/BJ20020793. Biochem J. 2002. PMID: 12033986 Free PMC article.

4

Application of multi-component reactions to antimalarial drug discovery. Part 1: Parallel synthesis and antiplasmodial activity of new 4-aminoquinoline Ugi adducts.

Musonda CC, Taylor D, Lehman J, Gut J, Rosenthal PJ, Chibale K. Musonda CC, et al. Among authors: taylor d. Bioorg Med Chem Lett. 2004 Aug 2;14(15):3901-5. doi: 10.1016/j.bmcl.2004.05.063. Bioorg Med Chem Lett. 2004. PMID: 15225694

5

A series of structurally simple chloroquine chemosensitizing dibemethin derivatives that inhibit chloroquine transport by PfCRT.

Zishiri VK, Hunter R, Smith PJ, Taylor D, Summers R, Kirk K, Martin RE, Egan TJ. Zishiri VK, et al. Among authors: taylor d. Eur J Med Chem. 2011 May;46(5):1729-42. doi: 10.1016/j.ejmech.2011.02.026. Epub 2011 Feb 22. Eur J Med Chem. 2011. PMID: 21396749

6

Synthesis, characterization and antimalarial activity of new chromium arene-quinoline half sandwich complexes.

Glans L, Taylor D, de Kock C, Smith PJ, Haukka M, Moss JR, Nordlander E. Glans L, et al. Among authors: taylor d. J Inorg Biochem. 2011 Jul;105(7):985-90. doi: 10.1016/j.jinorgbio.2011.03.019. Epub 2011 Apr 6. J Inorg Biochem. 2011. PMID: 21565148

7

Synthesis and evaluation of hybrid drugs for a potential HIV/AIDS-malaria combination therapy.

Aminake MN, Mahajan A, Kumar V, Hans R, Wiesner L, Taylor D, de Kock C, Grobler A, Smith PJ, Kirschner M, Rethwilm A, Pradel G, Chibale K. Aminake MN, et al. Among authors: taylor d. Bioorg Med Chem. 2012 Sep 1;20(17):5277-89. doi: 10.1016/j.bmc.2012.06.038. Epub 2012 Jun 29. Bioorg Med Chem. 2012. PMID: 22858300

8

Insights into the role of heme in the mechanism of action of antimalarials.

Combrinck JM, Mabotha TE, Ncokazi KK, Ambele MA, Taylor D, Smith PJ, Hoppe HC, Egan TJ. Combrinck JM, et al. Among authors: taylor d. ACS Chem Biol. 2013 Jan 18;8(1):133-7. doi: 10.1021/cb300454t. Epub 2012 Oct 11. ACS Chem Biol. 2013. PMID: 23043646 Free PMC article.

9

Synthesis, characterization, antiparasitic and cytotoxic evaluation of thioureas conjugated to polyamine scaffolds.

Stringer T, Taylor D, de Kock C, Guzgay H, Au A, An SH, Sanchez B, O'Connor R, Patel N, Land KM, Smith PJ, Hendricks DT, Egan TJ, Smith GS. Stringer T, et al. Among authors: taylor d. Eur J Med Chem. 2013 Nov;69:90-8. doi: 10.1016/j.ejmech.2013.08.004. Epub 2013 Aug 11. Eur J Med Chem. 2013. PMID: 24012713

10

In vitro antimalarial activity, β-haematin inhibition and structure-activity relationships in a series of quinoline triazoles.

Joshi MC, Wicht KJ, Taylor D, Hunter R, Smith PJ, Egan TJ. Joshi MC, et al. Among authors: taylor d. Eur J Med Chem. 2013 Nov;69:338-47. doi: 10.1016/j.ejmech.2013.08.046. Epub 2013 Sep 12. Eur J Med Chem. 2013. PMID: 24077524

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