Grail D - Search Results

1

Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling.

Jenkins BJ, Grail D, Nheu T, Najdovska M, Wang B, Waring P, Inglese M, McLoughlin RM, Jones SA, Topley N, Baumann H, Judd LM, Giraud AS, Boussioutas A, Zhu HJ, Ernst M. Jenkins BJ, et al. Among authors: grail d. Nat Med. 2005 Aug;11(8):845-52. doi: 10.1038/nm1282. Epub 2005 Jul 24. Nat Med. 2005. PMID: 16041381

2

Hematopoietic abnormalities in mice deficient in gp130-mediated STAT signaling.

Jenkins BJ, Quilici C, Roberts AW, Grail D, Dunn AR, Ernst M. Jenkins BJ, et al. Among authors: grail d. Exp Hematol. 2002 Nov;30(11):1248-56. doi: 10.1016/s0301-472x(02)00929-3. Exp Hematol. 2002. PMID: 12423677 Free article.

3

Imbalanced gp130-dependent signaling in macrophages alters macrophage colony-stimulating factor responsiveness via regulation of c-fms expression.

Jenkins BJ, Grail D, Inglese M, Quilici C, Bozinovski S, Wong P, Ernst M. Jenkins BJ, et al. Among authors: grail d. Mol Cell Biol. 2004 Feb;24(4):1453-63. doi: 10.1128/MCB.24.4.1453-1463.2004. Mol Cell Biol. 2004. PMID: 14749363 Free PMC article.

4

The threshold of gp130-dependent STAT3 signaling is critical for normal regulation of hematopoiesis.

Jenkins BJ, Roberts AW, Najdovska M, Grail D, Ernst M. Jenkins BJ, et al. Among authors: grail d. Blood. 2005 May 1;105(9):3512-20. doi: 10.1182/blood-2004-09-3751. Epub 2005 Jan 13. Blood. 2005. PMID: 15650055 Free article.

5

Pathologic consequences of STAT3 hyperactivation by IL-6 and IL-11 during hematopoiesis and lymphopoiesis.

Jenkins BJ, Roberts AW, Greenhill CJ, Najdovska M, Lundgren-May T, Robb L, Grail D, Ernst M. Jenkins BJ, et al. Among authors: grail d. Blood. 2007 Mar 15;109(6):2380-8. doi: 10.1182/blood-2006-08-040352. Epub 2006 Nov 2. Blood. 2007. PMID: 17082315 Free article.

6

STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice.

Ernst M, Najdovska M, Grail D, Lundgren-May T, Buchert M, Tye H, Matthews VB, Armes J, Bhathal PS, Hughes NR, Marcusson EG, Karras JG, Na S, Sedgwick JD, Hertzog PJ, Jenkins BJ. Ernst M, et al. Among authors: grail d. J Clin Invest. 2008 May;118(5):1727-38. doi: 10.1172/JCI34944. J Clin Invest. 2008. PMID: 18431520 Free PMC article.

7

Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice.

Tebbutt NC, Giraud AS, Inglese M, Jenkins B, Waring P, Clay FJ, Malki S, Alderman BM, Grail D, Hollande F, Heath JK, Ernst M. Tebbutt NC, et al. Among authors: grail d. Nat Med. 2002 Oct;8(10):1089-97. doi: 10.1038/nm763. Epub 2002 Sep 9. Nat Med. 2002. PMID: 12219085

8

Differential regulation of gastric tumor growth by cytokines that signal exclusively through the coreceptor gp130.

Howlett M, Judd LM, Jenkins B, La Gruta NL, Grail D, Ernst M, Giraud AS. Howlett M, et al. Among authors: grail d. Gastroenterology. 2005 Sep;129(3):1005-18. doi: 10.1053/j.gastro.2005.06.068. Gastroenterology. 2005. PMID: 16143138

9

IL-6 regulates neutrophil trafficking during acute inflammation via STAT3.

Fielding CA, McLoughlin RM, McLeod L, Colmont CS, Najdovska M, Grail D, Ernst M, Jones SA, Topley N, Jenkins BJ. Fielding CA, et al. Among authors: grail d. J Immunol. 2008 Aug 1;181(3):2189-95. doi: 10.4049/jimmunol.181.3.2189. J Immunol. 2008. PMID: 18641358

10

IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation.

McLoughlin RM, Jenkins BJ, Grail D, Williams AS, Fielding CA, Parker CR, Ernst M, Topley N, Jones SA. McLoughlin RM, et al. Among authors: grail d. Proc Natl Acad Sci U S A. 2005 Jul 5;102(27):9589-94. doi: 10.1073/pnas.0501794102. Epub 2005 Jun 23. Proc Natl Acad Sci U S A. 2005. PMID: 15976028 Free PMC article.

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