Carr RA - Search Results

1

Phase I safety, pharmacokinetic, and pharmacodynamic study of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 in patients with advanced cancer.

Hoekstra R, de Vos FY, Eskens FA, Gietema JA, van der Gaast A, Groen HJ, Knight RA, Carr RA, Humerickhouse RA, Verweij J, de Vries EG. Hoekstra R, et al. Among authors: carr ra. J Clin Oncol. 2005 Aug 1;23(22):5188-97. doi: 10.1200/JCO.2005.05.013. J Clin Oncol. 2005. PMID: 16051960 Clinical Trial.

2

A phase 1 trial of 2 dose schedules of ABT-510, an antiangiogenic, thrombospondin-1-mimetic peptide, in patients with advanced cancer.

Gordon MS, Mendelson D, Carr R, Knight RA, Humerickhouse RA, Iannone M, Stopeck AT. Gordon MS, et al. Among authors: carr r. Cancer. 2008 Dec 15;113(12):3420-9. doi: 10.1002/cncr.23953. Cancer. 2008. PMID: 18932258 Free article. Clinical Trial.

3

Phase I study of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 with 5-fluorouracil and leucovorin: a safe combination.

Hoekstra R, de Vos FY, Eskens FA, de Vries EG, Uges DR, Knight R, Carr RA, Humerickhouse R, Verweij J, Gietema JA. Hoekstra R, et al. Among authors: carr ra. Eur J Cancer. 2006 Mar;42(4):467-72. doi: 10.1016/j.ejca.2005.08.040. Epub 2006 Jan 10. Eur J Cancer. 2006. PMID: 16406507 Clinical Trial.

4

A phase I study assessing the safety and pharmacokinetics of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 with gemcitabine and cisplatin in patients with solid tumors.

Gietema JA, Hoekstra R, de Vos FY, Uges DR, van der Gaast A, Groen HJ, Loos WJ, Knight RA, Carr RA, Humerickhouse RA, Eskens FA. Gietema JA, et al. Among authors: carr ra. Ann Oncol. 2006 Aug;17(8):1320-7. doi: 10.1093/annonc/mdl102. Epub 2006 May 25. Ann Oncol. 2006. PMID: 16728485 Free article. Clinical Trial.

5

Randomized, phase II study of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 in patients with advanced soft tissue sarcoma.

Baker LH, Rowinsky EK, Mendelson D, Humerickhouse RA, Knight RA, Qian J, Carr RA, Gordon GB, Demetri GD. Baker LH, et al. Among authors: carr ra. J Clin Oncol. 2008 Dec 1;26(34):5583-8. doi: 10.1200/JCO.2008.17.4706. Epub 2008 Nov 3. J Clin Oncol. 2008. PMID: 18981463 Clinical Trial.

6

Phase I dose-escalation study of the safety and pharmacokinetics of atrasentan: an endothelin receptor antagonist for refractory prostate cancer.

Zonnenberg BA, Groenewegen G, Janus TJ, Leahy TW, Humerickhouse RA, Isaacson JD, Carr RA, Voest E. Zonnenberg BA, et al. Among authors: carr ra. Clin Cancer Res. 2003 Aug 1;9(8):2965-72. Clin Cancer Res. 2003. PMID: 12912943 Clinical Trial.

7

Dose-ranging study of the safety and pharmacokinetics of atrasentan in patients with refractory malignancies.

Ryan CW, Vogelzang NJ, Vokes EE, Kindler HL, Undevia SD, Humerickhouse R, André AK, Wang Q, Carr RA, Ratain MJ. Ryan CW, et al. Among authors: carr ra. Clin Cancer Res. 2004 Jul 1;10(13):4406-11. doi: 10.1158/1078-0432.CCR-04-0083. Clin Cancer Res. 2004. PMID: 15240529 Clinical Trial.

8

Atrasentan, an endothelin-receptor antagonist for refractory adenocarcinomas: safety and pharmacokinetics.

Carducci MA, Nelson JB, Bowling MK, Rogers T, Eisenberger MA, Sinibaldi V, Donehower R, Leahy TL, Carr RA, Isaacson JD, Janus TJ, Andre A, Hosmane BS, Padley RJ. Carducci MA, et al. Among authors: carr ra. J Clin Oncol. 2002 Apr 15;20(8):2171-80. doi: 10.1200/JCO.2002.08.028. J Clin Oncol. 2002. PMID: 11956279 Clinical Trial.

9

Phase 0 trials: an industry perspective.

Eliopoulos H, Giranda V, Carr R, Tiehen R, Leahy T, Gordon G. Eliopoulos H, et al. Clin Cancer Res. 2008 Jun 15;14(12):3683-8. doi: 10.1158/1078-0432.CCR-07-4586. Clin Cancer Res. 2008. PMID: 18559583

10

Dual effects of rifampin on the pharmacokinetics of atrasentan.

Xiong H, Carr RA, Locke CS, Katz DA, Achari R, Doan TT, Wang P, Jankowski JR, Sleep DJ. Xiong H, et al. Among authors: carr ra. J Clin Pharmacol. 2007 Apr;47(4):423-9. doi: 10.1177/0091270007299928. J Clin Pharmacol. 2007. PMID: 17389551 Clinical Trial.

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