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136 results

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Phase I safety, pharmacokinetic, and pharmacodynamic study of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 in patients with advanced cancer.
Hoekstra R, de Vos FY, Eskens FA, Gietema JA, van der Gaast A, Groen HJ, Knight RA, Carr RA, Humerickhouse RA, Verweij J, de Vries EG. Hoekstra R, et al. Among authors: van der gaast a. J Clin Oncol. 2005 Aug 1;23(22):5188-97. doi: 10.1200/JCO.2005.05.013. J Clin Oncol. 2005. PMID: 16051960 Clinical Trial.
Phase I and pharmacokinetic study of the dolastatin 10 analogue TZT-1027, given on days 1 and 8 of a 3-week cycle in patients with advanced solid tumors.
de Jonge MJ, van der Gaast A, Planting AS, van Doorn L, Lems A, Boot I, Wanders J, Satomi M, Verweij J. de Jonge MJ, et al. Among authors: van doorn l, van der gaast a. Clin Cancer Res. 2005 May 15;11(10):3806-13. doi: 10.1158/1078-0432.CCR-04-1937. Clin Cancer Res. 2005. PMID: 15897580 Clinical Trial.
Phase I and pharmacologic study of PKI166, an epidermal growth factor receptor tyrosine kinase inhibitor, in patients with advanced solid malignancies.
Hoekstra R, Dumez H, Eskens FA, van der Gaast A, Planting AS, de Heus G, Sizer KC, Ravera C, Vaidyanathan S, Bucana C, Fidler IJ, van Oosterom AT, Verweij J. Hoekstra R, et al. Among authors: van oosterom at, van der gaast a. Clin Cancer Res. 2005 Oct 1;11(19 Pt 1):6908-15. doi: 10.1158/1078-0432.CCR-05-0720. Clin Cancer Res. 2005. PMID: 16203782 Clinical Trial.
Phase I and pharmacokinetic study of brostallicin (PNU-166196), a new DNA minor-groove binder, administered intravenously every 3 weeks to adult patients with metastatic cancer.
Ten Tije AJ, Verweij J, Sparreboom A, Van Der Gaast A, Fowst C, Fiorentini F, Tursi J, Antonellini A, Mantel M, Hartman CM, Stoter G, Planting AS, De Jonge MJ. Ten Tije AJ, et al. Among authors: van der gaast a. Clin Cancer Res. 2003 Aug 1;9(8):2957-64. Clin Cancer Res. 2003. PMID: 12912942 Clinical Trial.
The potential of statins as part of anti-cancer treatment.
Sleijfer S, van der Gaast A, Planting AS, Stoter G, Verweij J. Sleijfer S, et al. Among authors: van der gaast a. Eur J Cancer. 2005 Mar;41(4):516-22. doi: 10.1016/j.ejca.2004.12.009. Epub 2005 Jan 11. Eur J Cancer. 2005. PMID: 15737555 Review.
Prophylaxis of irinotecan-induced diarrhea with neomycin and potential role for UGT1A1*28 genotype screening: a double-blind, randomized, placebo-controlled study.
de Jong FA, Kehrer DF, Mathijssen RH, Creemers GJ, de Bruijn P, van Schaik RH, Planting AS, van der Gaast A, Eskens FA, Janssen JT, Ruit JB, Verweij J, Sparreboom A, de Jonge MJ. de Jong FA, et al. Among authors: van der gaast a, van schaik rh. Oncologist. 2006 Sep;11(8):944-54. doi: 10.1634/theoncologist.11-8-944. Oncologist. 2006. PMID: 16951398 Free article. Clinical Trial.
Randomized Study on Dose Escalation in Definitive Chemoradiation for Patients With Locally Advanced Esophageal Cancer (ARTDECO Study).
Hulshof MCCM, Geijsen ED, Rozema T, Oppedijk V, Buijsen J, Neelis KJ, Nuyttens JJME, van der Sangen MJC, Jeene PM, Reinders JG, van Berge Henegouwen MI, Thano A, van Hooft JE, van Laarhoven HWM, van der Gaast A. Hulshof MCCM, et al. Among authors: van der gaast a. J Clin Oncol. 2021 Sep 1;39(25):2816-2824. doi: 10.1200/JCO.20.03697. Epub 2021 Jun 8. J Clin Oncol. 2021. PMID: 34101496 Clinical Trial.
136 results