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Page 1
Arg462Gln sequence variation in the prostate-cancer-susceptibility gene RNASEL and age of onset of hereditary non-polyposis colorectal cancer: a case-control study.
Krüger S, Silber AS, Engel C, Görgens H, Mangold E, Pagenstecher C, Holinski-Feder E, von Knebel Doeberitz M, Moeslein G, Dietmaier W, Stemmler S, Friedl W, Rüschoff J, Schackert HK; German Hereditary Non-Polyposis Colorectal Cancer Consortium. Krüger S, et al. Among authors: pagenstecher c. Lancet Oncol. 2005 Aug;6(8):566-72. doi: 10.1016/S1470-2045(05)70253-9. Lancet Oncol. 2005. PMID: 16054567
Eight novel MSH6 germline mutations in patients with familial and nonfamilial colorectal cancer selected by loss of protein expression in tumor tissue.
Plaschke J, Krüger S, Dietmaier W, Gebert J, Sutter C, Mangold E, Pagenstecher C, Holinski-Feder E, Schulmann K, Möslein G, Rüschoff J, Engel C, Evans G, Schackert HK; German HNPCC Consortium. Plaschke J, et al. Among authors: pagenstecher c. Hum Mutat. 2004 Mar;23(3):285. doi: 10.1002/humu.9217. Hum Mutat. 2004. PMID: 14974087
Lower incidence of colorectal cancer and later age of disease onset in 27 families with pathogenic MSH6 germline mutations compared with families with MLH1 or MSH2 mutations: the German Hereditary Nonpolyposis Colorectal Cancer Consortium.
Plaschke J, Engel C, Krüger S, Holinski-Feder E, Pagenstecher C, Mangold E, Moeslein G, Schulmann K, Gebert J, von Knebel Doeberitz M, Rüschoff J, Loeffler M, Schackert HK. Plaschke J, et al. Among authors: pagenstecher c. J Clin Oncol. 2004 Nov 15;22(22):4486-94. doi: 10.1200/JCO.2004.02.033. Epub 2004 Oct 13. J Clin Oncol. 2004. PMID: 15483016
N-acetyltransferase (NAT) 2 acetylator status and age of onset in patients with hereditary nonpolyposis colorectal cancer (HNPCC).
Pistorius S, Görgens H, Krüger S, Engel C, Mangold E, Pagenstecher C, Holinski-Feder E, Moeslein G, von Knebel Doeberitz M, Rüschoff J, Karner-Hanusch J, Saeger HD, Schackert HK; German Hnpcc-Consortium. Pistorius S, et al. Among authors: pagenstecher c. Cancer Lett. 2006 Sep 8;241(1):150-7. doi: 10.1016/j.canlet.2005.10.018. Epub 2005 Dec 6. Cancer Lett. 2006. PMID: 16337339
Absence of association between cyclin D1 (CCND1) G870A polymorphism and age of onset in hereditary nonpolyposis colorectal cancer.
Krüger S, Engel C, Bier A, Mangold E, Pagenstecher C, Doeberitz Mv, Holinski-Feder E, Moeslein G, Keller G, Kunstmann E, Friedl W, Plaschke J, Rüschoff J, Schackert HK; German HNPCC-Consortium. Krüger S, et al. Among authors: pagenstecher c. Cancer Lett. 2006 May 18;236(2):191-7. doi: 10.1016/j.canlet.2005.05.013. Cancer Lett. 2006. PMID: 16832876
The additive effect of p53 Arg72Pro and RNASEL Arg462Gln genotypes on age of disease onset in Lynch syndrome patients with pathogenic germline mutations in MSH2 or MLH1.
Krüger S, Engel C, Bier A, Silber AS, Görgens H, Mangold E, Pagenstecher C, Holinski-Feder E, von Knebel Doeberitz M, Royer-Pokora B, Dechant S, Pox C, Rahner N, Müller A, Schackert HK; German HNPCC Consortium. Krüger S, et al. Among authors: pagenstecher c. Cancer Lett. 2007 Jul 8;252(1):55-64. doi: 10.1016/j.canlet.2006.12.006. Epub 2007 Jan 16. Cancer Lett. 2007. PMID: 17224235
The p53 codon 72 variation is associated with the age of onset of hereditary non-polyposis colorectal cancer (HNPCC).
Krüger S, Bier A, Engel C, Mangold E, Pagenstecher C, von Knebel Doeberitz M, Holinski-Feder E, Moeslein G, Schulmann K, Plaschke J, Rüschoff J, Schackert HK; German Hereditary Non-Polyposis Colorectal Cancer Consortium. Krüger S, et al. Among authors: pagenstecher c. J Med Genet. 2005 Oct;42(10):769-73. doi: 10.1136/jmg.2004.028506. J Med Genet. 2005. PMID: 16199549 Free PMC article.
Microsatellite stable colorectal cancers in clinically suspected hereditary nonpolyposis colorectal cancer patients without vertical transmission of disease are unlikely to be caused by biallelic germline mutations in MYH.
Görgens H, Krüger S, Kuhlisch E, Pagenstecher C, Höhl R, Schackert HK, Müller A. Görgens H, et al. Among authors: pagenstecher c. J Mol Diagn. 2006 May;8(2):178-82. doi: 10.2353/jmoldx.2006.050119. J Mol Diagn. 2006. PMID: 16645203 Free PMC article.
HNPCC-associated small bowel cancer: clinical and molecular characteristics.
Schulmann K, Brasch FE, Kunstmann E, Engel C, Pagenstecher C, Vogelsang H, Krüger S, Vogel T, Knaebel HP, Rüschoff J, Hahn SA, Knebel-Doeberitz MV, Moeslein G, Meltzer SJ, Schackert HK, Tympner C, Mangold E, Schmiegel W; German HNPCC Consortium. Schulmann K, et al. Among authors: pagenstecher c. Gastroenterology. 2005 Mar;128(3):590-9. doi: 10.1053/j.gastro.2004.12.051. Gastroenterology. 2005. PMID: 15765394
Spectrum and frequencies of mutations in MSH2 and MLH1 identified in 1,721 German families suspected of hereditary nonpolyposis colorectal cancer.
Mangold E, Pagenstecher C, Friedl W, Mathiak M, Buettner R, Engel C, Loeffler M, Holinski-Feder E, Müller-Koch Y, Keller G, Schackert HK, Krüger S, Goecke T, Moeslein G, Kloor M, Gebert J, Kunstmann E, Schulmann K, Rüschoff J, Propping P. Mangold E, et al. Among authors: pagenstecher c. Int J Cancer. 2005 Sep 20;116(5):692-702. doi: 10.1002/ijc.20863. Int J Cancer. 2005. PMID: 15849733
29 results