Knoflach F - Search Results

1

9H-Xanthene-9-carboxylic acid [1,2,4]oxadiazol-3-yl- and (2H-tetrazol-5-yl)-amides as potent, orally available mGlu1 receptor enhancers.

Vieira E, Huwyler J, Jolidon S, Knoflach F, Mutel V, Wichmann J. Vieira E, et al. Among authors: knoflach f. Bioorg Med Chem Lett. 2005 Oct 15;15(20):4628-31. doi: 10.1016/j.bmcl.2005.05.135. Bioorg Med Chem Lett. 2005. PMID: 16099654

2

Multiple pathways for regulation of the KCl-induced [3H]-GABA release by metabotropic glutamate receptors, in primary rat cortical cultures.

Schaffhauser H, Knoflach F, Pink JR, Bleuel Z, Cartmell J, Goepfert F, Kemp JA, Richards JG, Adam G, Mutel V. Schaffhauser H, et al. Among authors: knoflach f. Brain Res. 1998 Jan 26;782(1-2):91-104. doi: 10.1016/s0006-8993(97)01271-7. Brain Res. 1998. PMID: 9519253

3

Effect of metabotropic glutamate receptor activation on receptor-mediated cyclic AMP responses in primary cultures of rat striatal neurones.

Cartmell J, Goepfert F, Knoflach F, Pink JR, Bleuel Z, Richards JG, Schaffhauser H, Kemp JA, Wichmann J, Mutel V. Cartmell J, et al. Among authors: knoflach f. Brain Res. 1998 Apr 27;791(1-2):191-9. doi: 10.1016/s0006-8993(98)00094-8. Brain Res. 1998. PMID: 9593890

4

Pharmacological properties of native metabotropic glutamate receptors in freshly dissociated Golgi cells of the rat cerebellum.

Knoflach F, Woltering T, Adam G, Mutel V, Kemp JA. Knoflach F, et al. Neuropharmacology. 2001;40(2):163-9. doi: 10.1016/s0028-3908(00)00152-0. Neuropharmacology. 2001. PMID: 11114394

5

Positive allosteric modulators of metabotropic glutamate 1 receptor: characterization, mechanism of action, and binding site.

Knoflach F, Mutel V, Jolidon S, Kew JN, Malherbe P, Vieira E, Wichmann J, Kemp JA. Knoflach F, et al. Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):13402-7. doi: 10.1073/pnas.231358298. Epub 2001 Oct 23. Proc Natl Acad Sci U S A. 2001. PMID: 11606768 Free PMC article.

6

Identification of essential residues involved in the glutamate binding pocket of the group II metabotropic glutamate receptor.

Malherbe P, Knoflach F, Broger C, Ohresser S, Kratzeisen C, Adam G, Stadler H, Kemp JA, Mutel V. Malherbe P, et al. Among authors: knoflach f. Mol Pharmacol. 2001 Nov;60(5):944-54. doi: 10.1124/mol.60.5.944. Mol Pharmacol. 2001. PMID: 11641422

7

Mutational analysis and molecular modeling of the allosteric binding site of a novel, selective, noncompetitive antagonist of the metabotropic glutamate 1 receptor.

Malherbe P, Kratochwil N, Knoflach F, Zenner MT, Kew JN, Kratzeisen C, Maerki HP, Adam G, Mutel V. Malherbe P, et al. Among authors: knoflach f. J Biol Chem. 2003 Mar 7;278(10):8340-7. doi: 10.1074/jbc.M211759200. Epub 2002 Dec 30. J Biol Chem. 2003. PMID: 12509432 Free article.

8

Identification and characterization of a novel splice variant of the metabotropic glutamate receptor 5 gene in human hippocampus and cerebellum.

Malherbe P, Kew JN, Richards JG, Knoflach F, Kratzeisen C, Zenner MT, Faull RL, Kemp JA, Mutel V. Malherbe P, et al. Among authors: knoflach f. Brain Res Mol Brain Res. 2002 Dec 30;109(1-2):168-78. doi: 10.1016/s0169-328x(02)00557-0. Brain Res Mol Brain Res. 2002. PMID: 12531526

9

Alkyl diphenylacetyl, 9H-xanthene- and 9H-thioxanthene-carbonyl carbamates as positive allosteric modulators of mGlu1 receptors.

Wichmann J, Bleicher K, Vieira E, Woltering T, Knoflach F, Mutel V. Wichmann J, et al. Among authors: knoflach f. Farmaco. 2002 Dec;57(12):989-92. doi: 10.1016/s0014-827x(02)01283-1. Farmaco. 2002. PMID: 12564473

10

Synthesis and characterization of 8-ethynyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one derivatives: new potent non-competitive metabotropic glutamate receptor 2/3 antagonists. Part 1.

Woltering TJ, Adam G, Alanine A, Wichmann J, Knoflach F, Mutel V, Gatti S. Woltering TJ, et al. Among authors: knoflach f. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6811-5. doi: 10.1016/j.bmcl.2007.10.026. Epub 2007 Oct 17. Bioorg Med Chem Lett. 2007. PMID: 17964783

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