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Page 1
Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis.
Camps M, Rückle T, Ji H, Ardissone V, Rintelen F, Shaw J, Ferrandi C, Chabert C, Gillieron C, Françon B, Martin T, Gretener D, Perrin D, Leroy D, Vitte PA, Hirsch E, Wymann MP, Cirillo R, Schwarz MK, Rommel C. Camps M, et al. Among authors: wymann mp. Nat Med. 2005 Sep;11(9):936-43. doi: 10.1038/nm1284. Epub 2005 Aug 28. Nat Med. 2005. PMID: 16127437 Free article.
Resistance to thromboembolism in PI3Kgamma-deficient mice.
Hirsch E, Bosco O, Tropel P, Laffargue M, Calvez R, Altruda F, Wymann M, Montrucchio G. Hirsch E, et al. FASEB J. 2001 Sep;15(11):2019-21. doi: 10.1096/fj.00-0810fje. Epub 2001 Jul 9. FASEB J. 2001. PMID: 11511514
Tumour biology. Weakening link to colorectal cancer?
Barbier M, Attoub S, Calvez R, Laffargue M, Jarry A, Mareel M, Altruda F, Gespach C, Wu D, Lu B, Hirsch E, Wymann MP. Barbier M, et al. Among authors: wymann mp. Nature. 2001 Oct 25;413(6858):796. doi: 10.1038/35101660. Nature. 2001. PMID: 11677595 No abstract available.
Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils.
Condliffe AM, Davidson K, Anderson KE, Ellson CD, Crabbe T, Okkenhaug K, Vanhaesebroeck B, Turner M, Webb L, Wymann MP, Hirsch E, Ruckle T, Camps M, Rommel C, Jackson SP, Chilvers ER, Stephens LR, Hawkins PT. Condliffe AM, et al. Among authors: wymann mp. Blood. 2005 Aug 15;106(4):1432-40. doi: 10.1182/blood-2005-03-0944. Epub 2005 May 5. Blood. 2005. PMID: 15878979 Free article.
PI(3)Kgamma has an important context-dependent role in neutrophil chemokinesis.
Ferguson GJ, Milne L, Kulkarni S, Sasaki T, Walker S, Andrews S, Crabbe T, Finan P, Jones G, Jackson S, Camps M, Rommel C, Wymann M, Hirsch E, Hawkins P, Stephens L. Ferguson GJ, et al. Nat Cell Biol. 2007 Jan;9(1):86-91. doi: 10.1038/ncb1517. Epub 2006 Dec 17. Nat Cell Biol. 2007. PMID: 17173040
134 results