Toth JI - Search Results

1

Blocking protein farnesyltransferase improves nuclear shape in fibroblasts from humans with progeroid syndromes.

Toth JI, Yang SH, Qiao X, Beigneux AP, Gelb MH, Moulson CL, Miner JH, Young SG, Fong LG. Toth JI, et al. Proc Natl Acad Sci U S A. 2005 Sep 6;102(36):12873-8. doi: 10.1073/pnas.0505767102. Epub 2005 Aug 29. Proc Natl Acad Sci U S A. 2005. PMID: 16129834 Free PMC article.

2

Blocking protein farnesyltransferase improves nuclear blebbing in mouse fibroblasts with a targeted Hutchinson-Gilford progeria syndrome mutation.

Yang SH, Bergo MO, Toth JI, Qiao X, Hu Y, Sandoval S, Meta M, Bendale P, Gelb MH, Young SG, Fong LG. Yang SH, et al. Among authors: toth ji. Proc Natl Acad Sci U S A. 2005 Jul 19;102(29):10291-6. doi: 10.1073/pnas.0504641102. Epub 2005 Jul 12. Proc Natl Acad Sci U S A. 2005. PMID: 16014412 Free PMC article.

3

Abnormal development of the cerebral cortex and cerebellum in the setting of lamin B2 deficiency.

Coffinier C, Chang SY, Nobumori C, Tu Y, Farber EA, Toth JI, Fong LG, Young SG. Coffinier C, et al. Among authors: toth ji. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5076-81. doi: 10.1073/pnas.0908790107. Epub 2010 Feb 9. Proc Natl Acad Sci U S A. 2010. PMID: 20145110 Free PMC article.

4

Selective coactivator interactions in gene activation by SREBP-1a and -1c.

Toth JI, Datta S, Athanikar JN, Freedman LP, Osborne TF. Toth JI, et al. Mol Cell Biol. 2004 Sep;24(18):8288-300. doi: 10.1128/MCB.24.18.8288-8300.2004. Mol Cell Biol. 2004. PMID: 15340088 Free PMC article.

5

A role for cyclic AMP response element-binding protein (CREB) but not the highly similar ATF-2 protein in sterol regulation of the promoter for 3-hydroxy-3-methylglutaryl coenzyme A reductase.

Ngo TT, Bennett MK, Bourgeois AL, Toth JI, Osborne TF. Ngo TT, et al. Among authors: toth ji. J Biol Chem. 2002 Sep 13;277(37):33901-5. doi: 10.1074/jbc.M202135200. Epub 2002 Jul 10. J Biol Chem. 2002. PMID: 12110665 Free article.

6

Selective association of sterol regulatory element-binding protein isoforms with target promoters in vivo.

Bennett MK, Toth JI, Osborne TF. Bennett MK, et al. Among authors: toth ji. J Biol Chem. 2004 Sep 3;279(36):37360-7. doi: 10.1074/jbc.M404693200. Epub 2004 Jun 25. J Biol Chem. 2004. PMID: 15220339 Free article.

7

Discovery of Monovalent Direct Degraders of BRD4 that Act via the Recruitment of DCAF11.

Parker GS, Toth JI, Fish S, Blanco G, Kampert T, Li X, Yang L, Stumpf CR, Steadman K, Jamborcic A, Chien S, Daniele E, Dearie A, Leriche G, Bailey S, Thompson PA. Parker GS, et al. Among authors: toth ji. Mol Cancer Ther. 2024 Jul 5:OF1-OF13. doi: 10.1158/1535-7163.MCT-24-0219. Online ahead of print. Mol Cancer Ther. 2024. PMID: 38967115

8

Discovery of Monovalent Direct Degraders of BRD4 That Act Via the Recruitment of DCAF11.

Parker GS, Toth JI, Fish S, Blanco GA, Kampert T, Li X, Yang L, Stumpf CR, Steadman K, Jamborcic A, Chien S, Daniele E, Dearie A, Leriche G, Bailey S, Thompson PA. Parker GS, et al. Among authors: toth ji. Mol Cancer Ther. 2024 Jun 22. doi: 10.1158/1535-7163.MCT-24-0219. Online ahead of print. Mol Cancer Ther. 2024. PMID: 38907538

9

Adapted ATPase domain communication overcomes the cytotoxicity of p97 inhibitors.

Wei Y, Toth JI, Blanco GA, Bobkov AA, Petroski MD. Wei Y, et al. Among authors: toth ji. J Biol Chem. 2018 Dec 28;293(52):20169-20180. doi: 10.1074/jbc.RA118.004301. Epub 2018 Oct 31. J Biol Chem. 2018. PMID: 30381397 Free PMC article.

10

p97 Composition Changes Caused by Allosteric Inhibition Are Suppressed by an On-Target Mechanism that Increases the Enzyme's ATPase Activity.

Her NG, Toth JI, Ma CT, Wei Y, Motamedchaboki K, Sergienko E, Petroski MD. Her NG, et al. Among authors: toth ji. Cell Chem Biol. 2016 Apr 21;23(4):517-28. doi: 10.1016/j.chembiol.2016.03.012. Cell Chem Biol. 2016. PMID: 27105284 Free PMC article.

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