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Benzodithiophenes potentiate differentiation of acute promyelocytic leukemia cells by lowering the threshold for ligand-mediated corepressor/coactivator exchange with retinoic acid receptor alpha and enhancing changes in all-trans-retinoic acid-regulated gene expression.
Xu K, Guidez F, Glasow A, Chung D, Petrie K, Stegmaier K, Wang KK, Zhang J, Jing Y, Zelent A, Waxman S. Xu K, et al. Among authors: guidez f. Cancer Res. 2005 Sep 1;65(17):7856-65. doi: 10.1158/0008-5472.CAN-05-1056. Cancer Res. 2005. PMID: 16140955
Rexinoid-triggered differentiation and tumor-selective apoptosis of acute myeloid leukemia by protein kinase A-mediated desubordination of retinoid X receptor.
Altucci L, Rossin A, Hirsch O, Nebbioso A, Vitoux D, Wilhelm E, Guidez F, De Simone M, Schiavone EM, Grimwade D, Zelent A, de Thé H, Gronemeyer H. Altucci L, et al. Among authors: guidez f. Cancer Res. 2005 Oct 1;65(19):8754-65. doi: 10.1158/0008-5472.CAN-04-3569. Cancer Res. 2005. PMID: 16204045
PLZF-RAR alpha fusion proteins generated from the variant t(11;17)(q23;q21) translocation in acute promyelocytic leukemia inhibit ligand-dependent transactivation of wild-type retinoic acid receptors.
Chen Z, Guidez F, Rousselot P, Agadir A, Chen SJ, Wang ZY, Degos L, Zelent A, Waxman S, Chomienne C. Chen Z, et al. Among authors: guidez f. Proc Natl Acad Sci U S A. 1994 Feb 1;91(3):1178-82. doi: 10.1073/pnas.91.3.1178. Proc Natl Acad Sci U S A. 1994. PMID: 8302850 Free PMC article.
Role of nuclear receptor corepressors in leukemogenesis.
Guidez F, Zelent A. Guidez F, et al. Curr Top Microbiol Immunol. 2001;254:165-85. doi: 10.1007/978-3-662-10595-5_9. Curr Top Microbiol Immunol. 2001. PMID: 11190573 Review. No abstract available.
The histone deacetylase 9 gene encodes multiple protein isoforms.
Petrie K, Guidez F, Howell L, Healy L, Waxman S, Greaves M, Zelent A. Petrie K, et al. Among authors: guidez f. J Biol Chem. 2003 May 2;278(18):16059-72. doi: 10.1074/jbc.M212935200. Epub 2003 Feb 17. J Biol Chem. 2003. PMID: 12590135 Free article.
Regulation of Hoxb2 by APL-associated PLZF protein.
Ivins S, Pemberton K, Guidez F, Howell L, Krumlauf R, Zelent A. Ivins S, et al. Among authors: guidez f. Oncogene. 2003 Jun 12;22(24):3685-97. doi: 10.1038/sj.onc.1206328. Oncogene. 2003. PMID: 12802276
54 results