Castagnoli N Jr - Search Results

1

Stereoelectronic and Resonance Effects on the Rate of Ring Opening of N-Cyclopropyl-Based Single Electron Transfer Probes.

Grimm ML, Suleman NK, Hancock AN, Spencer JN, Dudding T, Rowshanpour R, Castagnoli N Jr, Tanko JM. Grimm ML, et al. Among authors: castagnoli n jr. J Am Chem Soc. 2020 Feb 5;142(5):2640-2652. doi: 10.1021/jacs.9b12617. Epub 2020 Jan 22. J Am Chem Soc. 2020. PMID: 31913031

2

Evidence for a Proton-Coupled Electron Transfer Mechanism in a Biomimetic System for Monoamine Oxidase B Catalysis.

Nakamura A, Latif MA, Deck PA, Castagnoli N Jr, Tanko JM. Nakamura A, et al. Among authors: castagnoli n jr. Chemistry. 2020 Jan 16;26(4):823-829. doi: 10.1002/chem.201904634. Epub 2020 Jan 7. Chemistry. 2020. PMID: 31658386

3

Metabolism of Strained Rings: Glutathione S-transferase-Catalyzed Formation of a Glutathione-Conjugated Spiro-azetidine without Prior Bioactivation.

Li XQ, Grönberg G, Bangur EH, Hayes MA, Castagnoli N Jr, Weidolf L. Li XQ, et al. Among authors: castagnoli n jr. Drug Metab Dispos. 2019 Nov;47(11):1247-1256. doi: 10.1124/dmd.119.088658. Epub 2019 Sep 6. Drug Metab Dispos. 2019. PMID: 31492694

4

Discovery of a Novel Microsomal Epoxide Hydrolase-Catalyzed Hydration of a Spiro Oxetane.

Li XQ, Hayes MA, Grönberg G, Berggren K, Castagnoli N Jr, Weidolf L. Li XQ, et al. Among authors: castagnoli n jr. Drug Metab Dispos. 2016 Aug;44(8):1341-8. doi: 10.1124/dmd.116.071142. Epub 2016 Jun 2. Drug Metab Dispos. 2016. PMID: 27256986

5

Brain levels of the neurotoxic pyridinium metabolite HPP+ and extrapyramidal symptoms in haloperidol-treated mice.

Crowley JJ, Ashraf-Khorassani M, Castagnoli N Jr, Sullivan PF. Crowley JJ, et al. Among authors: castagnoli n jr. Neurotoxicology. 2013 Dec;39:153-7. doi: 10.1016/j.neuro.2013.09.005. Epub 2013 Oct 6. Neurotoxicology. 2013. PMID: 24107597 Free PMC article.

6

Bioactivation of the cannabinoid receptor antagonist rimonabant to a cytotoxic iminium ion metabolite.

Foster AJ, Prime LH, Gustafsson F, Temesi DG, Isin EM, Midlöv J, Castagnoli N Jr, Kenna JG. Foster AJ, et al. Among authors: castagnoli n jr. Chem Res Toxicol. 2013 Jan 18;26(1):124-35. doi: 10.1021/tx300418w. Epub 2012 Dec 12. Chem Res Toxicol. 2013. PMID: 23234359

7

Identification of the metabolites of lesogaberan using linear trap quadrupole orbitrap mass spectrometry and hydrophilic interaction liquid chromatography.

Ekdahl A, Aurell-Holmberg A, Castagnoli N Jr. Ekdahl A, et al. Among authors: castagnoli n jr. Xenobiotica. 2013 May;43(5):461-7. doi: 10.3109/00498254.2012.725486. Epub 2012 Oct 3. Xenobiotica. 2013. PMID: 23030741

8

Bioactivation pathways of the cannabinoid receptor 1 antagonist rimonabant.

Bergström MA, Isin EM, Castagnoli N Jr, Milne CE. Bergström MA, et al. Among authors: castagnoli n jr. Drug Metab Dispos. 2011 Oct;39(10):1823-32. doi: 10.1124/dmd.111.039412. Epub 2011 Jul 6. Drug Metab Dispos. 2011. PMID: 21733882

9

Reaction of benzophenone triplet with aliphatic amines. What a potent neurotoxin can tell us about the reaction mechanism.

Grimm ML, Allen WJ, Finn M, Castagnoli N Jr, Tanko JM. Grimm ML, et al. Among authors: castagnoli n jr. Bioorg Med Chem. 2011 Feb 15;19(4):1458-63. doi: 10.1016/j.bmc.2011.01.002. Epub 2011 Jan 7. Bioorg Med Chem. 2011. PMID: 21277784

10

Interactions of 1-methyl-3-phenylpyrrolidine and 3-methyl-1-phenyl-3-azabicyclo[3.1.0]hexane with monoamine oxidase B.

Pretorius A, Ogunrombi MO, Fourie H, Terre'blanche G, Castagnoli N Jr, Bergh JJ, Petzer JP. Pretorius A, et al. Among authors: castagnoli n jr. Bioorg Med Chem. 2010 Jun 1;18(11):4111-8. doi: 10.1016/j.bmc.2010.03.079. Epub 2010 Apr 3. Bioorg Med Chem. 2010. PMID: 20451395

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