Ceramide 1-phosphate is a direct activator of cytosolic phospholipase A2.
Pettus BJ, Bielawska A, Subramanian P, Wijesinghe DS, Maceyka M, Leslie CC, Evans JH, Freiberg J, Roddy P, Hannun YA, Chalfant CE.
Pettus BJ, et al. Among authors: bielawska a.
J Biol Chem. 2004 Mar 19;279(12):11320-6. doi: 10.1074/jbc.M309262200. Epub 2003 Dec 15.
J Biol Chem. 2004.
PMID: 14676210
Free article.
Recently, we demonstrated that ceramide kinase, and its product, ceramide 1-phosphate (Cer-1-P), were mediators of arachidonic acid released in cells in response to interleukin-1beta and calcium ionophore (Pettus, B. J., Bielawska, A., Spiegel, S., Roddy, P., Hannun …
Recently, we demonstrated that ceramide kinase, and its product, ceramide 1-phosphate (Cer-1-P), were mediators of arachidonic acid released …