Marzec M - Search Results

1

Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3.

Marzec M, Kasprzycka M, Ptasznik A, Wlodarski P, Zhang Q, Odum N, Wasik MA. Marzec M, et al. Lab Invest. 2005 Dec;85(12):1544-54. doi: 10.1038/labinvest.3700348. Lab Invest. 2005. PMID: 16170336 Free article.

2

Multi-gene epigenetic silencing of tumor suppressor genes in T-cell lymphoma cells; delayed expression of the p16 protein upon reversal of the silencing.

Nagasawa T, Zhang Q, Raghunath PN, Wong HY, El-Salem M, Szallasi A, Marzec M, Gimotty P, Rook AH, Vonderheid EC, Odum N, Wasik MA. Nagasawa T, et al. Among authors: marzec m. Leuk Res. 2006 Mar;30(3):303-12. doi: 10.1016/j.leukres.2005.08.012. Epub 2005 Sep 26. Leuk Res. 2006. PMID: 16185764

3

Oncogenic tyrosine kinase NPM/ALK induces activation of the MEK/ERK signaling pathway independently of c-Raf.

Marzec M, Kasprzycka M, Liu X, Raghunath PN, Wlodarski P, Wasik MA. Marzec M, et al. Oncogene. 2007 Feb 8;26(6):813-21. doi: 10.1038/sj.onc.1209843. Epub 2006 Aug 7. Oncogene. 2007. PMID: 16909118

4

Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway.

Marzec M, Kasprzycka M, Liu X, El-Salem M, Halasa K, Raghunath PN, Bucki R, Wlodarski P, Wasik MA. Marzec M, et al. Oncogene. 2007 Aug 16;26(38):5606-14. doi: 10.1038/sj.onc.1210346. Epub 2007 Mar 12. Oncogene. 2007. PMID: 17353907

5

Oncogenic kinase NPM/ALK induces expression of HIF1α mRNA.

Marzec M, Liu X, Wong W, Yang Y, Pasha T, Kantekure K, Zhang P, Woetmann A, Cheng M, Odum N, Wasik MA. Marzec M, et al. Oncogene. 2011 Mar 17;30(11):1372-8. doi: 10.1038/onc.2010.505. Epub 2010 Nov 22. Oncogene. 2011. PMID: 21102525

6

STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes.

Zhang Q, Wang HY, Marzec M, Raghunath PN, Nagasawa T, Wasik MA. Zhang Q, et al. Among authors: marzec m. Proc Natl Acad Sci U S A. 2005 May 10;102(19):6948-53. doi: 10.1073/pnas.0501959102. Epub 2005 May 3. Proc Natl Acad Sci U S A. 2005. PMID: 15870198 Free PMC article.

7

Activation of mammalian target of rapamycin in transformed B lymphocytes is nutrient dependent but independent of Akt, mitogen-activated protein kinase/extracellular signal-regulated kinase kinase, insulin growth factor-I, and serum.

Wlodarski P, Kasprzycka M, Liu X, Marzec M, Robertson ES, Slupianek A, Wasik MA. Wlodarski P, et al. Among authors: marzec m. Cancer Res. 2005 Sep 1;65(17):7800-8. doi: 10.1158/0008-5472.CAN-04-4180. Cancer Res. 2005. PMID: 16140948

8

Expression and oncogenic role of Brk (PTK6/Sik) protein tyrosine kinase in lymphocytes.

Kasprzycka M, Majewski M, Wang ZJ, Ptasznik A, Wysocka M, Zhang Q, Marzec M, Gimotty P, Crompton MR, Wasik MA. Kasprzycka M, et al. Among authors: marzec m. Am J Pathol. 2006 May;168(5):1631-41. doi: 10.2353/ajpath.2006.050521. Am J Pathol. 2006. PMID: 16651629 Free PMC article.

9

Mantle cell lymphoma cells express predominantly cyclin D1a isoform and are highly sensitive to selective inhibition of CDK4 kinase activity.

Marzec M, Kasprzycka M, Lai R, Gladden AB, Wlodarski P, Tomczak E, Nowell P, Deprimo SE, Sadis S, Eck S, Schuster SJ, Diehl JA, Wasik MA. Marzec M, et al. Blood. 2006 Sep 1;108(5):1744-50. doi: 10.1182/blood-2006-04-016634. Epub 2006 May 11. Blood. 2006. PMID: 16690963 Free PMC article.

10

Nucleophosmin/anaplastic lymphoma kinase (NPM/ALK) oncoprotein induces the T regulatory cell phenotype by activating STAT3.

Kasprzycka M, Marzec M, Liu X, Zhang Q, Wasik MA. Kasprzycka M, et al. Among authors: marzec m. Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9964-9. doi: 10.1073/pnas.0603507103. Epub 2006 Jun 9. Proc Natl Acad Sci U S A. 2006. PMID: 16766651 Free PMC article.

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