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Induction of broad and potent anti-human immunodeficiency virus immune responses in rhesus macaques by priming with a DNA vaccine and boosting with protein-adsorbed polylactide coglycolide microparticles.
Otten G, Schaefer M, Greer C, Calderon-Cacia M, Coit D, Kazzaz J, Medina-Selby A, Selby M, Singh M, Ugozzoli M, zur Megede J, Barnett SW, O'Hagan D, Donnelly J, Ulmer J. Otten G, et al. Among authors: donnelly j. J Virol. 2003 May;77(10):6087-92. doi: 10.1128/jvi.77.10.6087-6092.2003. J Virol. 2003. PMID: 12719603 Free PMC article.
Enhancement of DNA vaccine potency in rhesus macaques by electroporation.
Otten G, Schaefer M, Doe B, Liu H, Srivastava I, zur Megede J, O'Hagan D, Donnelly J, Widera G, Rabussay D, Lewis MG, Barnett S, Ulmer JB. Otten G, et al. Among authors: donnelly j. Vaccine. 2004 Jun 23;22(19):2489-93. doi: 10.1016/j.vaccine.2003.11.073. Vaccine. 2004. PMID: 15193413
Enhanced potency of plasmid DNA microparticle human immunodeficiency virus vaccines in rhesus macaques by using a priming-boosting regimen with recombinant proteins.
Otten GR, Schaefer M, Doe B, Liu H, Srivastava I, Megede Jz, Kazzaz J, Lian Y, Singh M, Ugozzoli M, Montefiori D, Lewis M, Driver DA, Dubensky T, Polo JM, Donnelly J, O'Hagan DT, Barnett S, Ulmer JB. Otten GR, et al. Among authors: donnelly j. J Virol. 2005 Jul;79(13):8189-200. doi: 10.1128/JVI.79.13.8189-8200.2005. J Virol. 2005. PMID: 15956564 Free PMC article.
Evaluation of human immunodeficiency virus type 1 subtype C gag, pol, and gagpol DNA and alphavirus replicon vaccines.
Megede JZ, Otten GR, Doe B, Liu H, Srivastava R, Greer C, Legg H, Tang T, Polo JM, Donnelly JJ, Ulmer JB, Barnett SW. Megede JZ, et al. Among authors: donnelly jj. Vaccine. 2006 Apr 5;24(15):2755-63. doi: 10.1016/j.vaccine.2006.01.013. Epub 2006 Jan 19. Vaccine. 2006. PMID: 16460840
These data are consistent with observations in non-human primates (Otten GR, Schaefer M, Doe B, Liu H, Magede JZ, Donnelly J, et al. Potent immunogenicity of an HIV-1 gag-pol fusion DNA vaccine delivered by in vivo electroporation. ...
These data are consistent with observations in non-human primates (Otten GR, Schaefer M, Doe B, Liu H, Magede JZ, Donnelly J, …
A therapeutic SIV DNA vaccine elicits T-cell immune responses, but no sustained control of viremia in SIVmac239-infected rhesus macaques.
zur Megede J, Sanders-Beer B, Silvera P, Golightly D, Bowlsbey A, Hebblewaite D, Sites D, Nieves-Duran L, Srivastava R, Otten GR, Rabussay D, Zhang L, Ulmer JB, Barnett SW, Donnelly JJ. zur Megede J, et al. Among authors: donnelly jj. AIDS Res Hum Retroviruses. 2008 Aug;24(8):1103-16. doi: 10.1089/aid.2008.0055. AIDS Res Hum Retroviruses. 2008. PMID: 18620495 Free PMC article.
Technical and regulatory hurdles for DNA vaccines.
Donnelly J, Berry K, Ulmer JB. Donnelly J, et al. Int J Parasitol. 2003 May;33(5-6):457-67. doi: 10.1016/s0020-7519(03)00056-0. Int J Parasitol. 2003. PMID: 12782047 Review.
Purification, characterization, and immunogenicity of a soluble trimeric envelope protein containing a partial deletion of the V2 loop derived from SF162, an R5-tropic human immunodeficiency virus type 1 isolate.
Srivastava IK, Stamatatos L, Kan E, Vajdy M, Lian Y, Hilt S, Martin L, Vita C, Zhu P, Roux KH, Vojtech L, C Montefiori D, Donnelly J, Ulmer JB, Barnett SW. Srivastava IK, et al. Among authors: donnelly j. J Virol. 2003 Oct;77(20):11244-59. doi: 10.1128/jvi.77.20.11244-11259.2003. J Virol. 2003. PMID: 14512572 Free PMC article.
1,661 results