Agar JN - Search Results

1

Proteasome activity or expression is not altered by activation of the heat shock transcription factor Hsf1 in cultured fibroblasts or myoblasts.

Taylor DM, Kabashi E, Agar JN, Minotti S, Durham HD. Taylor DM, et al. Among authors: agar jn. Cell Stress Chaperones. 2005 Autumn;10(3):230-41. doi: 10.1379/csc-119r.1. Cell Stress Chaperones. 2005. PMID: 16184768 Free PMC article.

2

Focal dysfunction of the proteasome: a pathogenic factor in a mouse model of amyotrophic lateral sclerosis.

Kabashi E, Agar JN, Taylor DM, Minotti S, Durham HD. Kabashi E, et al. Among authors: agar jn. J Neurochem. 2004 Jun;89(6):1325-35. doi: 10.1111/j.1471-4159.2004.02453.x. J Neurochem. 2004. PMID: 15189335 Free article.

3

Impaired proteasome function in sporadic amyotrophic lateral sclerosis.

Kabashi E, Agar JN, Strong MJ, Durham HD. Kabashi E, et al. Among authors: agar jn. Amyotroph Lateral Scler. 2012 Jun;13(4):367-71. doi: 10.3109/17482968.2012.686511. Amyotroph Lateral Scler. 2012. PMID: 22632443

4

Relevance of oxidative injury in the pathogenesis of motor neuron diseases.

Agar J, Durham H. Agar J, et al. Amyotroph Lateral Scler Other Motor Neuron Disord. 2003 Dec;4(4):232-42. doi: 10.1080/14660820310011278. Amyotroph Lateral Scler Other Motor Neuron Disord. 2003. PMID: 14753657 Review.

5

Overexpression of metallothionein protects cultured motor neurons against oxidative stress, but not mutant Cu/Zn-superoxide dismutase toxicity.

Taylor DM, Minotti S, Agar JN, Durham HD. Taylor DM, et al. Among authors: agar jn. Neurotoxicology. 2004 Sep;25(5):779-92. doi: 10.1016/j.neuro.2004.02.002. Neurotoxicology. 2004. PMID: 15288509

6

Tryptophan 32 potentiates aggregation and cytotoxicity of a copper/zinc superoxide dismutase mutant associated with familial amyotrophic lateral sclerosis.

Taylor DM, Gibbs BF, Kabashi E, Minotti S, Durham HD, Agar JN. Taylor DM, et al. Among authors: agar jn. J Biol Chem. 2007 Jun 1;282(22):16329-35. doi: 10.1074/jbc.M610119200. Epub 2007 Mar 27. J Biol Chem. 2007. PMID: 17389599 Free article.

7

Proteasomes remain intact, but show early focal alteration in their composition in a mouse model of amyotrophic lateral sclerosis.

Kabashi E, Agar JN, Hong Y, Taylor DM, Minotti S, Figlewicz DA, Durham HD. Kabashi E, et al. Among authors: agar jn. J Neurochem. 2008 Jun 1;105(6):2353-66. doi: 10.1111/j.1471-4159.2008.05317.x. J Neurochem. 2008. PMID: 18315558 Free article.

8

Artifacts to avoid while taking advantage of top-down mass spectrometry based detection of protein S-thiolation.

Auclair JR, Salisbury JP, Johnson JL, Petsko GA, Ringe D, Bosco DA, Agar NY, Santagata S, Durham HD, Agar JN. Auclair JR, et al. Among authors: agar jn, agar ny. Proteomics. 2014 May;14(10):1152-7. doi: 10.1002/pmic.201300450. Epub 2014 Apr 17. Proteomics. 2014. PMID: 24634066 Free PMC article.

9

Mutations in COX10 result in a defect in mitochondrial heme A biosynthesis and account for multiple, early-onset clinical phenotypes associated with isolated COX deficiency.

Antonicka H, Leary SC, Guercin GH, Agar JN, Horvath R, Kennaway NG, Harding CO, Jaksch M, Shoubridge EA. Antonicka H, et al. Among authors: agar jn. Hum Mol Genet. 2003 Oct 15;12(20):2693-702. doi: 10.1093/hmg/ddg284. Epub 2003 Aug 19. Hum Mol Genet. 2003. PMID: 12928484

10

Structural consequences of cysteinylation of Cu/Zn-superoxide dismutase.

Auclair JR, Brodkin HR, D'Aquino JA, Petsko GA, Ringe D, Agar JN. Auclair JR, et al. Among authors: agar jn. Biochemistry. 2013 Sep 10;52(36):6145-50. doi: 10.1021/bi400613h. Epub 2013 Aug 26. Biochemistry. 2013. PMID: 23919400 Free PMC article.

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