Kavanagh KL - Search Results

1

Structure of human phytanoyl-CoA 2-hydroxylase identifies molecular mechanisms of Refsum disease.

McDonough MA, Kavanagh KL, Butler D, Searls T, Oppermann U, Schofield CJ. McDonough MA, et al. Among authors: kavanagh kl. J Biol Chem. 2005 Dec 9;280(49):41101-10. doi: 10.1074/jbc.M507528200. Epub 2005 Sep 25. J Biol Chem. 2005. PMID: 16186124 Free article.

2

Crystal structure of PHYHD1A, a 2OG oxygenase related to phytanoyl-CoA hydroxylase.

Zhang Z, Kochan GT, Ng SS, Kavanagh KL, Oppermann U, Schofield CJ, McDonough MA. Zhang Z, et al. Among authors: kavanagh kl. Biochem Biophys Res Commun. 2011 May 20;408(4):553-8. doi: 10.1016/j.bbrc.2011.04.059. Epub 2011 Apr 21. Biochem Biophys Res Commun. 2011. PMID: 21530488

3

Reversible sequestration of active site cysteines in a 2Fe-2S-bridged dimer provides a mechanism for glutaredoxin 2 regulation in human mitochondria.

Johansson C, Kavanagh KL, Gileadi O, Oppermann U. Johansson C, et al. Among authors: kavanagh kl. J Biol Chem. 2007 Feb 2;282(5):3077-82. doi: 10.1074/jbc.M608179200. Epub 2006 Nov 22. J Biol Chem. 2007. PMID: 17121859 Free article.

4

Crystal structure of the 2-oxoglutarate- and Fe(II)-dependent lysyl hydroxylase JMJD6.

Mantri M, Krojer T, Bagg EA, Webby CJ, Butler DS, Kochan G, Kavanagh KL, Oppermann U, McDonough MA, Schofield CJ. Mantri M, et al. Among authors: kavanagh kl. J Mol Biol. 2010 Aug 13;401(2):211-22. J Mol Biol. 2010. PMID: 20684070

5

Structure and mechanism of human UDP-glucose 6-dehydrogenase.

Egger S, Chaikuad A, Kavanagh KL, Oppermann U, Nidetzky B. Egger S, et al. Among authors: kavanagh kl. J Biol Chem. 2011 Jul 8;286(27):23877-87. doi: 10.1074/jbc.M111.234682. Epub 2011 Apr 18. J Biol Chem. 2011. PMID: 21502315 Free PMC article.

6

Ribosomal oxygenases are structurally conserved from prokaryotes to humans.

Chowdhury R, Sekirnik R, Brissett NC, Krojer T, Ho CH, Ng SS, Clifton IJ, Ge W, Kershaw NJ, Fox GC, Muniz JRC, Vollmar M, Phillips C, Pilka ES, Kavanagh KL, von Delft F, Oppermann U, McDonough MA, Doherty AJ, Schofield CJ. Chowdhury R, et al. Among authors: kavanagh kl. Nature. 2014 Jun 19;510(7505):422-426. doi: 10.1038/nature13263. Epub 2014 May 11. Nature. 2014. PMID: 24814345 Free PMC article.

7

The crystal structure of human geranylgeranyl pyrophosphate synthase reveals a novel hexameric arrangement and inhibitory product binding.

Kavanagh KL, Dunford JE, Bunkoczi G, Russell RGG, Oppermann U. Kavanagh KL, et al. J Biol Chem. 2006 Aug 4;281(31):22004-22012. doi: 10.1074/jbc.M602603200. Epub 2006 May 11. J Biol Chem. 2006. PMID: 16698791 Free article.

8

Crystal structure of the PHF8 Jumonji domain, an Nepsilon-methyl lysine demethylase.

Yue WW, Hozjan V, Ge W, Loenarz C, Cooper CD, Schofield CJ, Kavanagh KL, Oppermann U, McDonough MA. Yue WW, et al. Among authors: kavanagh kl. FEBS Lett. 2010 Feb 19;584(4):825-30. doi: 10.1016/j.febslet.2009.12.055. Epub 2010 Jan 12. FEBS Lett. 2010. PMID: 20067792 Free article.

9

Crystal Structure of the 2-Oxoglutarate- and Fe(II)-Dependent Lysyl Hydroxylase JMJD6.

Mantri M, Krojer T, Bagg EA, Webby CA, Butler DS, Kochan G, Kavanagh KL, Oppermann U, McDonough MA, Schofield CJ. Mantri M, et al. Among authors: kavanagh kl. J Mol Biol. 2010 May 31. doi: 10.1016/j.jmb.2010.05.054. Online ahead of print. J Mol Biol. 2010. PMID: 20685276

10

Structural and kinetic evidence that catalytic reaction of human UDP-glucose 6-dehydrogenase involves covalent thiohemiacetal and thioester enzyme intermediates.

Egger S, Chaikuad A, Klimacek M, Kavanagh KL, Oppermann U, Nidetzky B. Egger S, et al. Among authors: kavanagh kl. J Biol Chem. 2012 Jan 13;287(3):2119-29. doi: 10.1074/jbc.M111.313015. Epub 2011 Nov 28. J Biol Chem. 2012. PMID: 22123821 Free PMC article.

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