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A human monoclonal antibody neutralizes diverse HIV-1 isolates by binding a critical gp41 epitope.
Miller MD, Geleziunas R, Bianchi E, Lennard S, Hrin R, Zhang H, Lu M, An Z, Ingallinella P, Finotto M, Mattu M, Finnefrock AC, Bramhill D, Cook J, Eckert DM, Hampton R, Patel M, Jarantow S, Joyce J, Ciliberto G, Cortese R, Lu P, Strohl W, Schleif W, McElhaugh M, Lane S, Lloyd C, Lowe D, Osbourn J, Vaughan T, Emini E, Barbato G, Kim PS, Hazuda DJ, Shiver JW, Pessi A. Miller MD, et al. Among authors: finnefrock ac. Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14759-64. doi: 10.1073/pnas.0506927102. Epub 2005 Oct 3. Proc Natl Acad Sci U S A. 2005. PMID: 16203977 Free PMC article.
Affinity maturation and characterization of a human monoclonal antibody against HIV-1 gp41.
Montgomery DL, Wang YJ, Hrin R, Luftig M, Su B, Miller MD, Wang F, Haytko P, Huang L, Vitelli S, Condra J, Liu X, Hampton R, Carfi A, Pessi A, Bianchi E, Joyce J, Lloyd C, Geleziunas R, Bramhill D, King VM, Finnefrock AC, Strohl W, An Z. Montgomery DL, et al. Among authors: finnefrock ac. MAbs. 2009 Sep-Oct;1(5):462-74. doi: 10.4161/mabs.1.5.9214. Epub 2009 Sep 8. MAbs. 2009. PMID: 20065653 Free PMC article.
Vaccination with peptide mimetics of the gp41 prehairpin fusion intermediate yields neutralizing antisera against HIV-1 isolates.
Bianchi E, Joyce JG, Miller MD, Finnefrock AC, Liang X, Finotto M, Ingallinella P, McKenna P, Citron M, Ottinger E, Hepler RW, Hrin R, Nahas D, Wu C, Montefiori D, Shiver JW, Pessi A, Kim PS. Bianchi E, et al. Among authors: finnefrock ac. Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10655-60. doi: 10.1073/pnas.1004261107. Epub 2010 May 18. Proc Natl Acad Sci U S A. 2010. PMID: 20483992 Free PMC article.
Pentameric complex of viral glycoprotein H is the primary target for potent neutralization by a human cytomegalovirus vaccine.
Freed DC, Tang Q, Tang A, Li F, He X, Huang Z, Meng W, Xia L, Finnefrock AC, Durr E, Espeseth AS, Casimiro DR, Zhang N, Shiver JW, Wang D, An Z, Fu TM. Freed DC, et al. Among authors: finnefrock ac. Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):E4997-5005. doi: 10.1073/pnas.1316517110. Epub 2013 Dec 2. Proc Natl Acad Sci U S A. 2013. PMID: 24297878 Free PMC article.
Vectored Gag and Env but not Tat show efficacy against simian-human immunodeficiency virus 89.6P challenge in Mamu-A*01-negative rhesus monkeys.
Liang X, Casimiro DR, Schleif WA, Wang F, Davies ME, Zhang ZQ, Fu TM, Finnefrock AC, Handt L, Citron MP, Heidecker G, Tang A, Chen M, Wilson KA, Gabryelski L, McElhaugh M, Carella A, Moyer C, Huang L, Vitelli S, Patel D, Lin J, Emini EA, Shiver JW. Liang X, et al. Among authors: finnefrock ac. J Virol. 2005 Oct;79(19):12321-31. doi: 10.1128/JVI.79.19.12321-12331.2005. J Virol. 2005. PMID: 16160159 Free PMC article.
A fully human monoclonal antibody to Staphylococcus aureus iron regulated surface determinant B (IsdB) with functional activity in vitro and in vivo.
Ebert T, Smith S, Pancari G, Clark D, Hampton R, Secore S, Towne V, Fan H, Wang XM, Wu X, Ernst R, Harvey BR, Finnefrock AC, Wang F, Tan C, Durr E, Cope L, Anderson A, An Z, McNeely T. Ebert T, et al. Among authors: finnefrock ac. Hum Antibodies. 2010;19(4):113-28. doi: 10.3233/HAB-2010-0235. Hum Antibodies. 2010. PMID: 21178283
34 results