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Page 1
Synthesis and structure-activity relationships of beta- and alpha-piperidine sulfone hydroxamic acid matrix metalloproteinase inhibitors with oral antitumor efficacy.
Becker DP, Villamil CI, Barta TE, Bedell LJ, Boehm TL, Decrescenzo GA, Freskos JN, Getman DP, Hockerman S, Heintz R, Howard SC, Li MH, McDonald JJ, Carron CP, Funckes-Shippy CL, Mehta PP, Munie GE, Swearingen CA. Becker DP, et al. Among authors: getman dp. J Med Chem. 2005 Oct 20;48(21):6713-30. doi: 10.1021/jm0500875. J Med Chem. 2005. PMID: 16220987
alpha-Amino-beta-sulphone hydroxamates as potent MMP-13 inhibitors that spare MMP-1.
Becker DP, Barta TE, Bedell L, DeCrescenzo G, Freskos J, Getman DP, Hockerman SL, Li M, Mehta P, Mischke B, Munie GE, Swearingen C, Villamil CI. Becker DP, et al. Among authors: getman dp. Bioorg Med Chem Lett. 2001 Oct 22;11(20):2719-22. doi: 10.1016/s0960-894x(01)00556-x. Bioorg Med Chem Lett. 2001. PMID: 11591509
Discovery of novel benzothiazolesulfonamides as potent inhibitors of HIV-1 protease.
Nagarajan SR, De Crescenzo GA, Getman DP, Lu HF, Sikorski JA, Walker JL, McDonald JJ, Houseman KA, Kocan GP, Kishore N, Mehta PP, Funkes-Shippy CL, Blystone L. Nagarajan SR, et al. Among authors: getman dp. Bioorg Med Chem. 2003 Nov 3;11(22):4769-77. doi: 10.1016/j.bmc.2003.07.001. Bioorg Med Chem. 2003. PMID: 14556792
Conformationally constrained [p-(omega-aminoalkyl)phenacetyl]-L-seryl-L-lysyl dipeptide amides as potent peptidomimetic inhibitors of Candida albicans and human myristoyl-CoA:protein N-myristoyl transferase.
Nagarajan SR, Devadas B, Zupec ME, Freeman SK, Brown DL, Lu HF, Mehta PP, Kishore NS, McWherter CA, Getman DP, Gordon JI, Sikorski JA. Nagarajan SR, et al. Among authors: getman dp. J Med Chem. 1997 May 9;40(10):1422-38. doi: 10.1021/jm9608671. J Med Chem. 1997. PMID: 9154965
SC-52151, a novel inhibitor of the human immunodeficiency virus protease.
Bryant M, Getman D, Smidt M, Marr J, Clare M, Dillard R, Lansky D, DeCrescenzo G, Heintz R, Houseman K, et al. Bryant M, et al. Antimicrob Agents Chemother. 1995 Oct;39(10):2229-34. doi: 10.1128/AAC.39.10.2229. Antimicrob Agents Chemother. 1995. PMID: 8619573 Free PMC article.
Design and synthesis of novel imidazole-substituted dipeptide amides as potent and selective inhibitors of Candida albicans myristoylCoA:protein N-myristoyltransferase and identification of related tripeptide inhibitors with mechanism-based antifungal activity.
Devadas B, Freeman SK, Zupec ME, Lu HF, Nagarajan SR, Kishore NS, Lodge JK, Kuneman DW, McWherter CA, Vinjamoori DV, Getman DP, Gordon JI, Sikorski JA. Devadas B, et al. Among authors: getman dp. J Med Chem. 1997 Aug 1;40(16):2609-25. doi: 10.1021/jm970094w. J Med Chem. 1997. PMID: 9258368
20 results