Mattingly RR - Search Results

1

The mitogen-activated protein kinase/extracellular signal-regulated kinase kinase inhibitor PD184352 (CI-1040) selectively induces apoptosis in malignant schwannoma cell lines.

Mattingly RR, Kraniak JM, Dilworth JT, Mathieu P, Bealmear B, Nowak JE, Benjamins JA, Tainsky MA, Reiners JJ Jr. Mattingly RR, et al. J Pharmacol Exp Ther. 2006 Jan;316(1):456-65. doi: 10.1124/jpet.105.091454. Epub 2005 Oct 20. J Pharmacol Exp Ther. 2006. PMID: 16239399

2

Potent suppression of proliferation of a10 vascular smooth muscle cells by combined treatment with lovastatin and 3-allylfarnesol, an inhibitor of protein farnesyltransferase.

Mattingly RR, Gibbs RA, Menard RE, Reiners JJ Jr. Mattingly RR, et al. J Pharmacol Exp Ther. 2002 Oct;303(1):74-81. doi: 10.1124/jpet.102.036061. J Pharmacol Exp Ther. 2002. PMID: 12235235

3

Mitogen-activated protein kinase signaling in drug-resistant neuroblastoma cells.

Mattingly RR. Mattingly RR. Methods Mol Biol. 2003;218:71-83. doi: 10.1385/1-59259-356-9:71. Methods Mol Biol. 2003. PMID: 12616713

4

Cell surface receptors activate p21-activated kinase 1 via multiple Ras and PI3-kinase-dependent pathways.

Menard RE, Mattingly RR. Menard RE, et al. Among authors: mattingly rr. Cell Signal. 2003 Dec;15(12):1099-109. doi: 10.1016/s0898-6568(03)00087-1. Cell Signal. 2003. PMID: 14575865

5

Gbetagamma subunits stimulate p21-activated kinase 1 (PAK1) through activation of PI3-kinase and Akt but act independently of Rac1/Cdc42.

Menard RE, Mattingly RR. Menard RE, et al. Among authors: mattingly rr. FEBS Lett. 2004 Jan 2;556(1-3):187-92. doi: 10.1016/s0014-5793(03)01406-6. FEBS Lett. 2004. PMID: 14706848 Free article.

6

TNF-alpha-mediated apoptosis in normal human prostate epithelial cells and tumor cell lines.

Chopra DP, Menard RE, Januszewski J, Mattingly RR. Chopra DP, et al. Among authors: mattingly rr. Cancer Lett. 2004 Jan 20;203(2):145-54. doi: 10.1016/j.canlet.2003.09.016. Cancer Lett. 2004. PMID: 14732222

7

Active p21-activated kinase 1 rescues MCF10A breast epithelial cells from undergoing anoikis.

Menard RE, Jovanovski AP, Mattingly RR. Menard RE, et al. Among authors: mattingly rr. Neoplasia. 2005 Jul;7(7):638-45. doi: 10.1593/neo.04736. Neoplasia. 2005. PMID: 16026643 Free PMC article.

8

Molecular targets for emerging anti-tumor therapies for neurofibromatosis type 1.

Dilworth JT, Kraniak JM, Wojtkowiak JW, Gibbs RA, Borch RF, Tainsky MA, Reiners JJ Jr, Mattingly RR. Dilworth JT, et al. Among authors: mattingly rr. Biochem Pharmacol. 2006 Nov 30;72(11):1485-92. doi: 10.1016/j.bcp.2006.04.010. Epub 2006 Apr 28. Biochem Pharmacol. 2006. PMID: 16797490 Review.

9

Synthesis, biochemical, and cellular evaluation of farnesyl monophosphate prodrugs as farnesyltransferase inhibitors.

Clark MK, Scott SA, Wojtkowiak J, Chirco R, Mathieu P, Reiners JJ Jr, Mattingly RR, Borch RF, Gibbs RA. Clark MK, et al. Among authors: mattingly rr. J Med Chem. 2007 Jul 12;50(14):3274-82. doi: 10.1021/jm0701829. Epub 2007 Jun 8. J Med Chem. 2007. PMID: 17555307

10

Induction of apoptosis in neurofibromatosis type 1 malignant peripheral nerve sheath tumor cell lines by a combination of novel farnesyl transferase inhibitors and lovastatin.

Wojtkowiak JW, Fouad F, LaLonde DT, Kleinman MD, Gibbs RA, Reiners JJ Jr, Borch RF, Mattingly RR. Wojtkowiak JW, et al. Among authors: mattingly rr. J Pharmacol Exp Ther. 2008 Jul;326(1):1-11. doi: 10.1124/jpet.107.135830. Epub 2008 Mar 26. J Pharmacol Exp Ther. 2008. PMID: 18367665 Free PMC article.

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