Sussman JL - Search Results

1

Inhibition of acetylcholinesterase by the anticancer prodrug CPT-11.

Hyatt JL, Tsurkan L, Morton CL, Yoon KJ, Harel M, Brumshtein B, Silman I, Sussman JL, Wadkins RM, Potter PM. Hyatt JL, et al. Among authors: sussman jl. Chem Biol Interact. 2005 Dec 15;157-158:247-52. doi: 10.1016/j.cbi.2005.10.033. Epub 2005 Oct 28. Chem Biol Interact. 2005. PMID: 16257398

2

Conversion of acetylcholinesterase to butyrylcholinesterase: modeling and mutagenesis.

Harel M, Sussman JL, Krejci E, Bon S, Chanal P, Massoulié J, Silman I. Harel M, et al. Among authors: sussman jl. Proc Natl Acad Sci U S A. 1992 Nov 15;89(22):10827-31. doi: 10.1073/pnas.89.22.10827. Proc Natl Acad Sci U S A. 1992. PMID: 1438284 Free PMC article.

3

Atomic structure of acetylcholinesterase from Torpedo californica: a prototypic acetylcholine-binding protein.

Sussman JL, Harel M, Frolow F, Oefner C, Goldman A, Toker L, Silman I. Sussman JL, et al. Science. 1991 Aug 23;253(5022):872-9. doi: 10.1126/science.1678899. Science. 1991. PMID: 1678899

4

Refined crystal structures of "aged" and "non-aged" organophosphoryl conjugates of gamma-chymotrypsin.

Harel M, Su CT, Frolow F, Ashani Y, Silman I, Sussman JL. Harel M, et al. Among authors: sussman jl. J Mol Biol. 1991 Oct 5;221(3):909-18. doi: 10.1016/0022-2836(91)80183-u. J Mol Biol. 1991. PMID: 1942036

5

Purification and crystallization of a dimeric form of acetylcholinesterase from Torpedo californica subsequent to solubilization with phosphatidylinositol-specific phospholipase C.

Sussman JL, Harel M, Frolow F, Varon L, Toker L, Futerman AH, Silman I. Sussman JL, et al. J Mol Biol. 1988 Oct 5;203(3):821-3. doi: 10.1016/0022-2836(88)90213-6. J Mol Biol. 1988. PMID: 2850366

6

Three-dimensional structures of acetylcholinesterase and of its complexes with anticholinesterase agents.

Silman I, Harel M, Axelsen P, Raves M, Sussman JL. Silman I, et al. Among authors: sussman jl. Biochem Soc Trans. 1994 Aug;22(3):745-9. doi: 10.1042/bst0220745. Biochem Soc Trans. 1994. PMID: 7821677 Review. No abstract available.

7

A metastable state of Torpedo californica acetylcholinesterase generated by modification with organomercurials.

Kreimer DI, Dolginova EA, Raves M, Sussman JL, Silman I, Weiner L. Kreimer DI, et al. Among authors: sussman jl. Biochemistry. 1994 Dec 6;33(48):14407-18. doi: 10.1021/bi00252a006. Biochemistry. 1994. PMID: 7981200

8

Structure and dynamics of the active site gorge of acetylcholinesterase: synergistic use of molecular dynamics simulation and X-ray crystallography.

Axelsen PH, Harel M, Silman I, Sussman JL. Axelsen PH, et al. Among authors: sussman jl. Protein Sci. 1994 Feb;3(2):188-97. doi: 10.1002/pro.5560030204. Protein Sci. 1994. PMID: 8003956 Free PMC article.

9

Differential effects of "peripheral" site ligands on Torpedo and chicken acetylcholinesterase.

Eichler J, Anselment A, Sussman JL, Massoulié J, Silman I. Eichler J, et al. Among authors: sussman jl. Mol Pharmacol. 1994 Feb;45(2):335-40. Mol Pharmacol. 1994. PMID: 8114681

10

Structure and functions of acetylcholinesterase and butyrylcholinesterase.

Massoulié J, Sussman J, Bon S, Silman I. Massoulié J, et al. Prog Brain Res. 1993;98:139-46. doi: 10.1016/s0079-6123(08)62391-2. Prog Brain Res. 1993. PMID: 8248501 Review. No abstract available.

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