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In vitro gamma-secretase cleavage of the Alzheimer's amyloid precursor protein correlates to a subset of presenilin complexes and is inhibited by zinc.
FEBS J. 2005 Nov;272(21):5544-57. doi: 10.1111/j.1742-4658.2005.04950.x.
FEBS J. 2005.
PMID: 16262694
Free article.
Characterization of presenilin complexes from mouse and human brain using Blue Native gel electrophoresis reveals high expression in embryonic brain and minimal change in complex mobility with pathogenic presenilin mutations.
Culvenor JG, Ilaya NT, Ryan MT, Canterford L, Hoke DE, Williamson NA, McLean CA, Masters CL, Evin G.
Culvenor JG, et al. Among authors: ilaya nt.
Eur J Biochem. 2004 Jan;271(2):375-85. doi: 10.1046/j.1432-1033.2003.03936.x.
Eur J Biochem. 2004.
PMID: 14717705
Free article.
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Nicastrin expression in mouse peripheral tissues is not co-ordinated with presenilin and is high in muscle.
Ilaya NT, Evin G, Masters CL, Culvenor JG.
Ilaya NT, et al.
J Neurochem. 2004 Oct;91(1):230-7. doi: 10.1111/j.1471-4159.2004.02718.x.
J Neurochem. 2004.
PMID: 15379903
Free article.
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