Chan PS - Search Results

1

Pyridobenzodiazepines: a novel class of orally active, vasopressin V2 receptor selective agonists.

Failli AA, Shumsky JS, Steffan RJ, Caggiano TJ, Williams DK, Trybulski EJ, Ning X, Lock Y, Tanikella T, Hartmann D, Chan PS, Park CH. Failli AA, et al. Among authors: chan ps. Bioorg Med Chem Lett. 2006 Feb 15;16(4):954-9. doi: 10.1016/j.bmcl.2005.10.107. Epub 2005 Nov 15. Bioorg Med Chem Lett. 2006. PMID: 16297621

2

(4-Substituted-phenyl)-(5H-10,11-dihydro-pyrrolo [2,1-c][1,4] benzodiazepin-10-yl)-methanone derivatives as vasopressin receptor modulators.

Venkatesan AM, Grosu GT, Failli AA, Chan PS, Coupet J, Saunders T, Mazandarani H, Ru X. Venkatesan AM, et al. Among authors: chan ps. Bioorg Med Chem Lett. 2005 Nov 15;15(22):5003-6. doi: 10.1016/j.bmcl.2005.08.007. Bioorg Med Chem Lett. 2005. PMID: 16153837

3

The design, synthesis and physical chemical properties of novel human vasopressin V2-receptor antagonists optimized for parenteral delivery.

Ashwell MA, Bagli JF, Caggiano TJ, Chan PS, Molinari AJ, Palka C, Park CH, Rogers JF, Sherman M, Trybulski EJ, Williams DK. Ashwell MA, et al. Among authors: chan ps. Bioorg Med Chem Lett. 2000 Apr 17;10(8):783-6. doi: 10.1016/s0960-894x(00)00095-0. Bioorg Med Chem Lett. 2000. PMID: 10782686

4

Structure-activity study of novel tricyclic benzazepine arginine vasopressin antagonists.

Sum FW, Dusza J, Santos ED, Grosu G, Reich M, Du X, Albright JD, Chan P, Coupet J, Ru X, Mazandarani H, Saunders T. Sum FW, et al. Bioorg Med Chem Lett. 2003 Jul 7;13(13):2195-8. doi: 10.1016/s0960-894x(03)00388-3. Bioorg Med Chem Lett. 2003. PMID: 12798333

5

VPA-985, a nonpeptide orally active and selective vasopressin V2 receptor antagonist.

Chan PS, Coupet J, Park HC, Lai F, Hartupee D, Cervoni P, Dusza JP, Albright JD, Ru X, Mazandarani H, Tanikella T, Shepherd C, Ochalski L, Bailey T, Lock TY, Ning X, Taylor JR, Spinelli W. Chan PS, et al. Adv Exp Med Biol. 1998;449:439-43. doi: 10.1007/978-1-4615-4871-3_55. Adv Exp Med Biol. 1998. PMID: 10026835 Review. No abstract available.

6

4,10-dihydro-5H-thieno[3,2-c][1]benzazepine derivatives and 9,10-dihydro-4H-thieno[2,3-c][1]benzazepine derivatives as orally active arginine vasopressin receptor antagonists.

Aranapakam V, Albright JD, Grosu GT, Chan PS, Coupet J, Saunders T, Ru X, Mazandarani H. Aranapakam V, et al. Among authors: chan ps. Bioorg Med Chem Lett. 1999 Jul 5;9(13):1733-6. doi: 10.1016/s0960-894x(99)00278-4. Bioorg Med Chem Lett. 1999. PMID: 10406632

7

The synthesis and vasopressin (AVP) antagonist activity of a novel series of N-aroyl-2,4,5,6-tetrahydropyrazolo[3,4-d]thieno[3,2-b]azepines.

Albright JD, Delos Santos EG, Dusza JP, Chan PS, Coupet J, Ru X, Mazandarani H. Albright JD, et al. Among authors: chan ps. Bioorg Med Chem Lett. 2000 Apr 17;10(8):695-8. doi: 10.1016/s0960-894x(00)00084-6. Bioorg Med Chem Lett. 2000. PMID: 10782666

8

5-Fluoro-2-methyl-N-[4-(5H-pyrrolo[2,1-c]-[1, 4]benzodiazepin-10(11H)-ylcarbonyl)-3-chlorophenyl]benzamide (VPA-985): an orally active arginine vasopressin antagonist with selectivity for V2 receptors.

Albright JD, Reich MF, Delos Santos EG, Dusza JP, Sum FW, Venkatesan AM, Coupet J, Chan PS, Ru X, Mazandarani H, Bailey T. Albright JD, et al. Among authors: chan ps. J Med Chem. 1998 Jul 2;41(14):2442-4. doi: 10.1021/jm980179c. J Med Chem. 1998. PMID: 9651149 Clinical Trial. No abstract available.

9

5-fluoro-2-methyl-N-[5-(5H-pyrrolo[2,1-c][1,4]benzodiazepine-10(11H)-yl carbonyl)-2-pyridinyl]benzamide (CL-385004) and analogs as orally active arginine vasopressin receptor antagonists.

Aranapakam V, Albright JD, Grosu GT, Delos Santos EG, Chan PS, Coupet J, Ru X, Saunders T, Mazandarani H. Aranapakam V, et al. Among authors: chan ps. Bioorg Med Chem Lett. 1999 Jul 5;9(13):1737-40. doi: 10.1016/s0960-894x(99)00279-6. Bioorg Med Chem Lett. 1999. PMID: 10406633

10

Effects of different stages of aortic coarctation hypertension on aortic contraction and relaxation in rats.

Lai FM, Tanikella T, Thibault L, Chan PS, Cervoni P. Lai FM, et al. Among authors: chan ps. J Pharmacol Exp Ther. 1980 Aug;214(2):388-94. J Pharmacol Exp Ther. 1980. PMID: 6993660

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