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Calmodulin is involved in the Ca2+-dependent activation of ceramide kinase as a calcium sensor.
Mitsutake S, Igarashi Y. Mitsutake S, et al. J Biol Chem. 2005 Dec 9;280(49):40436-41. doi: 10.1074/jbc.M501962200. Epub 2005 Oct 3. J Biol Chem. 2005. PMID: 16203736 Free article.
We recently demonstrated that the activation of ceramide kinase (CERK) and the formation of its product, ceramide 1-phosphate (C1P), are necessary for the degranulation pathway in mast cells and that the kinase activity of this enzyme is completely dependent on the intracellular …
We recently demonstrated that the activation of ceramide kinase (CERK) and the formation of its product, ceramide 1-phosphate (C1P), are nec …
Ceramide kinase is not essential but might act as an Ca2+-sensor for mast cell activation.
Mitsutake S, Kumada H, Soga M, Hurue Y, Asanuma F, Nagira M, Deguchi M, Date T, Yokose U, Inagaki Y, Sugiura M, Kohama T, Igarashi Y. Mitsutake S, et al. Prostaglandins Other Lipid Mediat. 2010 Nov;93(3-4):109-12. doi: 10.1016/j.prostaglandins.2010.07.003. Epub 2010 Aug 1. Prostaglandins Other Lipid Mediat. 2010. PMID: 20678580
106 results