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Page 1
The mutational spectrum of PTPN11 in juvenile myelomonocytic leukemia and Noonan syndrome/myeloproliferative disease.
Kratz CP, Niemeyer CM, Castleberry RP, Cetin M, Bergsträsser E, Emanuel PD, Hasle H, Kardos G, Klein C, Kojima S, Stary J, Trebo M, Zecca M, Gelb BD, Tartaglia M, Loh ML. Kratz CP, et al. Among authors: emanuel pd. Blood. 2005 Sep 15;106(6):2183-5. doi: 10.1182/blood-2005-02-0531. Epub 2005 May 31. Blood. 2005. PMID: 15928039 Free PMC article.
Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis.
Loh ML, Vattikuti S, Schubbert S, Reynolds MG, Carlson E, Lieuw KH, Cheng JW, Lee CM, Stokoe D, Bonifas JM, Curtiss NP, Gotlib J, Meshinchi S, Le Beau MM, Emanuel PD, Shannon KM. Loh ML, et al. Among authors: emanuel pd. Blood. 2004 Mar 15;103(6):2325-31. doi: 10.1182/blood-2003-09-3287. Epub 2003 Nov 26. Blood. 2004. PMID: 14644997 Free article.
Development of an allele-specific minimal residual disease assay for patients with juvenile myelomonocytic leukemia.
Archambeault S, Flores NJ, Yoshimi A, Kratz CP, Reising M, Fischer A, Noellke P, Locatelli F, Sedlacek P, Flotho C, Zecca M, Emanuel PD, Castleberry RP, Niemeyer CM, Bader P, Loh ML. Archambeault S, et al. Among authors: emanuel pd. Blood. 2008 Feb 1;111(3):1124-7. doi: 10.1182/blood-2007-06-093302. Epub 2007 Nov 13. Blood. 2008. PMID: 18000165 Free PMC article.
Mutations in CBL occur frequently in juvenile myelomonocytic leukemia.
Loh ML, Sakai DS, Flotho C, Kang M, Fliegauf M, Archambeault S, Mullighan CG, Chen L, Bergstraesser E, Bueso-Ramos CE, Emanuel PD, Hasle H, Issa JP, van den Heuvel-Eibrink MM, Locatelli F, Stary J, Trebo M, Wlodarski M, Zecca M, Shannon KM, Niemeyer CM. Loh ML, et al. Among authors: emanuel pd. Blood. 2009 Aug 27;114(9):1859-63. doi: 10.1182/blood-2009-01-198416. Epub 2009 Jul 1. Blood. 2009. PMID: 19571318 Free PMC article.
Mutations in GATA2 are rare in juvenile myelomonocytic leukemia.
Stieglitz E, Liu YL, Emanuel PD, Castleberry RP, Cooper TM, Shannon KM, Loh ML. Stieglitz E, et al. Among authors: emanuel pd. Blood. 2014 Feb 27;123(9):1426-7. doi: 10.1182/blood-2013-11-531079. Blood. 2014. PMID: 24578498 Free PMC article. No abstract available.
Subclonal mutations in SETBP1 confer a poor prognosis in juvenile myelomonocytic leukemia.
Stieglitz E, Troup CB, Gelston LC, Haliburton J, Chow ED, Yu KB, Akutagawa J, Taylor-Weiner AN, Liu YL, Wang YD, Beckman K, Emanuel PD, Braun BS, Abate A, Gerbing RB, Alonzo TA, Loh ML. Stieglitz E, et al. Among authors: emanuel pd. Blood. 2015 Jan 15;125(3):516-24. doi: 10.1182/blood-2014-09-601690. Epub 2014 Nov 13. Blood. 2015. PMID: 25395418 Free PMC article.
Phase II/III trial of a pre-transplant farnesyl transferase inhibitor in juvenile myelomonocytic leukemia: a report from the Children's Oncology Group.
Stieglitz E, Ward AF, Gerbing RB, Alonzo TA, Arceci RJ, Liu YL, Emanuel PD, Widemann BC, Cheng JW, Jayaprakash N, Balis FM, Castleberry RP, Bunin NJ, Loh ML, Cooper TM. Stieglitz E, et al. Among authors: emanuel pd. Pediatr Blood Cancer. 2015 Apr;62(4):629-36. doi: 10.1002/pbc.25342. Epub 2014 Dec 8. Pediatr Blood Cancer. 2015. PMID: 25704135 Free PMC article. Clinical Trial.
75 results