Melchor L - Search Results

1

The accumulation of specific amplifications characterizes two different genomic pathways of evolution of familial breast tumors.

Melchor L, Alvarez S, Honrado E, Palacios J, Barroso A, Díez O, Osorio A, Benítez J. Melchor L, et al. Clin Cancer Res. 2005 Dec 15;11(24 Pt 1):8577-84. doi: 10.1158/1078-0432.CCR-05-1278. Clin Cancer Res. 2005. PMID: 16361540

2

Distinct genomic aberration patterns are found in familial breast cancer associated with different immunohistochemical subtypes.

Melchor L, Honrado E, García MJ, Alvarez S, Palacios J, Osorio A, Nathanson KL, Benítez J. Melchor L, et al. Oncogene. 2008 May 15;27(22):3165-75. doi: 10.1038/sj.onc.1210975. Epub 2007 Dec 10. Oncogene. 2008. PMID: 18071313

3

A predictor based on the somatic genomic changes of the BRCA1/BRCA2 breast cancer tumors identifies the non-BRCA1/BRCA2 tumors with BRCA1 promoter hypermethylation.

Alvarez S, Diaz-Uriarte R, Osorio A, Barroso A, Melchor L, Paz MF, Honrado E, Rodríguez R, Urioste M, Valle L, Díez O, Cigudosa JC, Dopazo J, Esteller M, Benitez J. Alvarez S, et al. Among authors: melchor l. Clin Cancer Res. 2005 Feb 1;11(3):1146-53. Clin Cancer Res. 2005. PMID: 15709182

4

Genomic analysis of the 8p11-12 amplicon in familial breast cancer.

Melchor L, Garcia MJ, Honrado E, Pole JC, Alvarez S, Edwards PA, Caldas C, Brenton JD, Benítez J. Melchor L, et al. Int J Cancer. 2007 Feb 1;120(3):714-7. doi: 10.1002/ijc.22354. Int J Cancer. 2007. PMID: 17096335

5

Immunohistochemical classification of non-BRCA1/2 tumors identifies different groups that demonstrate the heterogeneity of BRCAX families.

Honrado E, Osorio A, Milne RL, Paz MF, Melchor L, Cascón A, Urioste M, Cazorla A, Díez O, Lerma E, Esteller M, Palacios J, Benítez J. Honrado E, et al. Among authors: melchor l. Mod Pathol. 2007 Dec;20(12):1298-306. doi: 10.1038/modpathol.3800969. Epub 2007 Sep 21. Mod Pathol. 2007. PMID: 17885670 Free article.

6

Estrogen receptor status could modulate the genomic pattern in familial and sporadic breast cancer.

Melchor L, Honrado E, Huang J, Alvarez S, Naylor TL, García MJ, Osorio A, Blesa D, Stratton MR, Weber BL, Cigudosa JC, Rahman N, Nathanson KL, Benítez J. Melchor L, et al. Clin Cancer Res. 2007 Dec 15;13(24):7305-13. doi: 10.1158/1078-0432.CCR-07-0711. Clin Cancer Res. 2007. PMID: 18094411

7

An integrative hypothesis about the origin and development of sporadic and familial breast cancer subtypes.

Melchor L, Benítez J. Melchor L, et al. Carcinogenesis. 2008 Aug;29(8):1475-82. doi: 10.1093/carcin/bgn157. Epub 2008 Jul 1. Carcinogenesis. 2008. PMID: 18596026 Review.

8

The complex genetic landscape of familial breast cancer.

Melchor L, Benítez J. Melchor L, et al. Hum Genet. 2013 Aug;132(8):845-63. doi: 10.1007/s00439-013-1299-y. Epub 2013 Apr 5. Hum Genet. 2013. PMID: 23552954 Review.

9

A haplotype containing the p53 polymorphisms Ins16bp and Arg72Pro modifies cancer risk in BRCA2 mutation carriers.

Osorio A, Martínez-Delgado B, Pollán M, Cuadros M, Urioste M, Torrenteras C, Melchor L, Díez O, De La Hoya M, Velasco E, González-Sarmiento R, Caldés T, Alonso C, Benítez J. Osorio A, et al. Among authors: melchor l. Hum Mutat. 2006 Mar;27(3):242-8. doi: 10.1002/humu.20283. Hum Mutat. 2006. PMID: 16419081

10

Comprehensive characterization of the DNA amplification at 13q34 in human breast cancer reveals TFDP1 and CUL4A as likely candidate target genes.

Melchor L, Saucedo-Cuevas LP, Muñoz-Repeto I, Rodríguez-Pinilla SM, Honrado E, Campoverde A, Palacios J, Nathanson KL, García MJ, Benítez J. Melchor L, et al. Breast Cancer Res. 2009;11(6):R86. doi: 10.1186/bcr2456. Epub 2009 Dec 8. Breast Cancer Res. 2009. PMID: 19995430 Free PMC article.

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