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Page 1
Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes.
Frahm N, Kiepiela P, Adams S, Linde CH, Hewitt HS, Sango K, Feeney ME, Addo MM, Lichterfeld M, Lahaie MP, Pae E, Wurcel AG, Roach T, St John MA, Altfeld M, Marincola FM, Moore C, Mallal S, Carrington M, Heckerman D, Allen TM, Mullins JI, Korber BT, Goulder PJ, Walker BD, Brander C. Frahm N, et al. Nat Immunol. 2006 Feb;7(2):173-8. doi: 10.1038/ni1281. Epub 2005 Dec 20. Nat Immunol. 2006. PMID: 16369537
Consistent cytotoxic-T-lymphocyte targeting of immunodominant regions in human immunodeficiency virus across multiple ethnicities.
Frahm N, Korber BT, Adams CM, Szinger JJ, Draenert R, Addo MM, Feeney ME, Yusim K, Sango K, Brown NV, SenGupta D, Piechocka-Trocha A, Simonis T, Marincola FM, Wurcel AG, Stone DR, Russell CJ, Adolf P, Cohen D, Roach T, StJohn A, Khatri A, Davis K, Mullins J, Goulder PJ, Walker BD, Brander C. Frahm N, et al. J Virol. 2004 Mar;78(5):2187-200. doi: 10.1128/jvi.78.5.2187-2200.2004. J Virol. 2004. PMID: 14963115 Free PMC article.
Comprehensive analysis of human immunodeficiency virus type 1-specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptides.
Kaufmann DE, Bailey PM, Sidney J, Wagner B, Norris PJ, Johnston MN, Cosimi LA, Addo MM, Lichterfeld M, Altfeld M, Frahm N, Brander C, Sette A, Walker BD, Rosenberg ES. Kaufmann DE, et al. Among authors: frahm n. J Virol. 2004 May;78(9):4463-77. doi: 10.1128/jvi.78.9.4463-4477.2004. J Virol. 2004. PMID: 15078927 Free PMC article.
Differences in the expressed HLA class I alleles effect the differential clustering of HIV type 1-specific T cell responses in infected Chinese and caucasians.
Yu XG, Addo MM, Perkins BA, Wej F, Rathod A, Geer SC, Parta M, Cohen D, Stone DR, Russell CJ, Tanzi G, Mei S, Wurcel AG, Frahm N, Lichterfeld M, Heath L, Mullins JI, Marincola F, Goulder PJ, Brander C, Allen T, Cao Y, Walker BD, Altfeld M. Yu XG, et al. Among authors: frahm n. AIDS Res Hum Retroviruses. 2004 May;20(5):557-64. doi: 10.1089/088922204323087813. AIDS Res Hum Retroviruses. 2004. PMID: 15186531
IL-8 responsiveness defines a subset of CD8 T cells poised to kill.
Hess C, Means TK, Autissier P, Woodberry T, Altfeld M, Addo MM, Frahm N, Brander C, Walker BD, Luster AD. Hess C, et al. Among authors: frahm n. Blood. 2004 Dec 1;104(12):3463-71. doi: 10.1182/blood-2004-03-1067. Epub 2004 Aug 3. Blood. 2004. PMID: 15292066 Free article.
The majority of currently circulating human immunodeficiency virus type 1 clade B viruses fail to prime cytotoxic T-lymphocyte responses against an otherwise immunodominant HLA-A2-restricted epitope: implications for vaccine design.
Altfeld M, Allen TM, Kalife ET, Frahm N, Addo MM, Mothe BR, Rathod A, Reyor LL, Harlow J, Yu XG, Perkins B, Robinson LK, Sidney J, Alter G, Lichterfeld M, Sette A, Rosenberg ES, Goulder PJ, Brander C, Walker BD. Altfeld M, et al. Among authors: frahm n. J Virol. 2005 Apr;79(8):5000-5. doi: 10.1128/JVI.79.8.5000-5005.2005. J Virol. 2005. PMID: 15795285 Free PMC article.
Simultaneous assessment of cytotoxic T lymphocyte responses against multiple viral infections by combined usage of optimal epitope matrices, anti- CD3 mAb T-cell expansion and "RecycleSpot".
Bihl FK, Loggi E, Chisholm JV 3rd, Hewitt HS, Henry LM, Linde C, Suscovich TJ, Wong JT, Frahm N, Andreone P, Brander C. Bihl FK, et al. Among authors: frahm n. J Transl Med. 2005 May 11;3(1):20. doi: 10.1186/1479-5876-3-20. J Transl Med. 2005. PMID: 15888204 Free PMC article.
HLA-B63 presents HLA-B57/B58-restricted cytotoxic T-lymphocyte epitopes and is associated with low human immunodeficiency virus load.
Frahm N, Adams S, Kiepiela P, Linde CH, Hewitt HS, Lichterfeld M, Sango K, Brown NV, Pae E, Wurcel AG, Altfeld M, Feeney ME, Allen TM, Roach T, St John MA, Daar ES, Rosenberg E, Korber B, Marincola F, Walker BD, Goulder PJ, Brander C. Frahm N, et al. J Virol. 2005 Aug;79(16):10218-25. doi: 10.1128/JVI.79.16.10218-10225.2005. J Virol. 2005. PMID: 16051815 Free PMC article.
De novo generation of escape variant-specific CD8+ T-cell responses following cytotoxic T-lymphocyte escape in chronic human immunodeficiency virus type 1 infection.
Allen TM, Yu XG, Kalife ET, Reyor LL, Lichterfeld M, John M, Cheng M, Allgaier RL, Mui S, Frahm N, Alter G, Brown NV, Johnston MN, Rosenberg ES, Mallal SA, Brander C, Walker BD, Altfeld M. Allen TM, et al. Among authors: frahm n. J Virol. 2005 Oct;79(20):12952-60. doi: 10.1128/JVI.79.20.12952-12960.2005. J Virol. 2005. PMID: 16188997 Free PMC article.
152 results