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Randomized pharmacokinetic and pharmacodynamic study of docetaxel: dosing based on body-surface area compared with individualized dosing based on cytochrome P450 activity estimated using a urinary metabolite of exogenous cortisol.
Yamamoto N, Tamura T, Murakami H, Shimoyama T, Nokihara H, Ueda Y, Sekine I, Kunitoh H, Ohe Y, Kodama T, Shimizu M, Nishio K, Ishizuka N, Saijo N. Yamamoto N, et al. Among authors: shimoyama t. J Clin Oncol. 2005 Feb 20;23(6):1061-9. doi: 10.1200/JCO.2005.11.036. Epub 2005 Jan 18. J Clin Oncol. 2005. PMID: 15657405 Clinical Trial.
Translational studies for target-based drugs.
Nishio K, Arao T, Shimoyama T, Fujiwara Y, Tamura T, Saijo N. Nishio K, et al. Among authors: shimoyama t. Cancer Chemother Pharmacol. 2005 Nov;56 Suppl 1:90-3. doi: 10.1007/s00280-005-0104-6. Cancer Chemother Pharmacol. 2005. PMID: 16273363 Review.
Phase I and pharmacokinetic study of edotecarin, a novel topoisomerase I inhibitor, administered once every 3 weeks in patients with solid tumors.
Yamada Y, Tamura T, Yamamoto N, Shimoyama T, Ueda Y, Murakami H, Kusaba H, Kamiya Y, Saka H, Tanigawara Y, McGovren JP, Natsumeda Y. Yamada Y, et al. Among authors: shimoyama t. Cancer Chemother Pharmacol. 2006 Aug;58(2):173-82. doi: 10.1007/s00280-005-0149-6. Epub 2005 Nov 25. Cancer Chemother Pharmacol. 2006. PMID: 16308697 Clinical Trial.
796 results