Voskoboinik I - Search Results

1

Addressing the mysteries of perforin function.

Voskoboinik I, Trapani JA. Voskoboinik I, et al. Immunol Cell Biol. 2006 Feb;84(1):66-71. doi: 10.1111/j.1440-1711.2005.01409.x. Immunol Cell Biol. 2006. PMID: 16405653 Review.

2

The functional basis for hemophagocytic lymphohistiocytosis in a patient with co-inherited missense mutations in the perforin (PFN1) gene.

Voskoboinik I, Thia MC, De Bono A, Browne K, Cretney E, Jackson JT, Darcy PK, Jane SM, Smyth MJ, Trapani JA. Voskoboinik I, et al. J Exp Med. 2004 Sep 20;200(6):811-6. doi: 10.1084/jem.20040776. Epub 2004 Sep 14. J Exp Med. 2004. PMID: 15365097 Free PMC article.

3

Calcium-dependent plasma membrane binding and cell lysis by perforin are mediated through its C2 domain: A critical role for aspartate residues 429, 435, 483, and 485 but not 491.

Voskoboinik I, Thia MC, Fletcher J, Ciccone A, Browne K, Smyth MJ, Trapani JA. Voskoboinik I, et al. J Biol Chem. 2005 Mar 4;280(9):8426-34. doi: 10.1074/jbc.M413303200. Epub 2004 Dec 2. J Biol Chem. 2005. PMID: 15576364 Free article.

4

A functional analysis of the putative polymorphisms A91V and N252S and 22 missense perforin mutations associated with familial hemophagocytic lymphohistiocytosis.

Voskoboinik I, Thia MC, Trapani JA. Voskoboinik I, et al. Blood. 2005 Jun 15;105(12):4700-6. doi: 10.1182/blood-2004-12-4935. Epub 2005 Mar 8. Blood. 2005. PMID: 15755897 Free article.

5

Perforin-mediated target-cell death and immune homeostasis.

Voskoboinik I, Smyth MJ, Trapani JA. Voskoboinik I, et al. Nat Rev Immunol. 2006 Dec;6(12):940-52. doi: 10.1038/nri1983. Nat Rev Immunol. 2006. PMID: 17124515 Review.

6

Apoptosis induced by the lymphocyte effector molecule perforin.

Bolitho P, Voskoboinik I, Trapani JA, Smyth MJ. Bolitho P, et al. Among authors: voskoboinik i. Curr Opin Immunol. 2007 Jun;19(3):339-47. doi: 10.1016/j.coi.2007.04.007. Epub 2007 Apr 17. Curr Opin Immunol. 2007. PMID: 17442557 Review.

7

The complex issue of regulating perforin expression.

Trapani JA, Voskoboinik I. Trapani JA, et al. Among authors: voskoboinik i. Trends Immunol. 2007 Jun;28(6):243-5. doi: 10.1016/j.it.2007.04.003. Epub 2007 Apr 27. Trends Immunol. 2007. PMID: 17466595 Review.

8

Perforin activity and immune homeostasis: the common A91V polymorphism in perforin results in both presynaptic and postsynaptic defects in function.

Voskoboinik I, Sutton VR, Ciccone A, House CM, Chia J, Darcy PK, Yagita H, Trapani JA. Voskoboinik I, et al. Blood. 2007 Aug 15;110(4):1184-90. doi: 10.1182/blood-2007-02-072850. Epub 2007 May 2. Blood. 2007. PMID: 17475905 Free article.

9

Infective, neoplastic, and homeostatic sequelae of the loss of perforin function in humans.

Trapani JA, Voskoboinik I. Trapani JA, et al. Among authors: voskoboinik i. Adv Exp Med Biol. 2007;601:235-42. doi: 10.1007/978-0-387-72005-0_24. Adv Exp Med Biol. 2007. PMID: 17713010 Review.

10

A common fold mediates vertebrate defense and bacterial attack.

Rosado CJ, Buckle AM, Law RH, Butcher RE, Kan WT, Bird CH, Ung K, Browne KA, Baran K, Bashtannyk-Puhalovich TA, Faux NG, Wong W, Porter CJ, Pike RN, Ellisdon AM, Pearce MC, Bottomley SP, Emsley J, Smith AI, Rossjohn J, Hartland EL, Voskoboinik I, Trapani JA, Bird PI, Dunstone MA, Whisstock JC. Rosado CJ, et al. Among authors: voskoboinik i. Science. 2007 Sep 14;317(5844):1548-51. doi: 10.1126/science.1144706. Epub 2007 Aug 23. Science. 2007. PMID: 17717151

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