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Modifying Rap1-signalling by targeting Pde6δ is neuroprotective in models of Alzheimer's disease.
Dumbacher M, Van Dooren T, Princen K, De Witte K, Farinelli M, Lievens S, Tavernier J, Dehaen W, Wera S, Winderickx J, Allasia S, Kilonda A, Spieser S, Marchand A, Chaltin P, Hoogenraad CC, Griffioen G. Dumbacher M, et al. Among authors: wera s. Mol Neurodegener. 2018 Sep 26;13(1):50. doi: 10.1186/s13024-018-0283-3. Mol Neurodegener. 2018. PMID: 30257685 Free PMC article.
Neuronal or glial expression of human apolipoprotein e4 affects parenchymal and vascular amyloid pathology differentially in different brain regions of double- and triple-transgenic mice.
Van Dooren T, Muyllaert D, Borghgraef P, Cresens A, Devijver H, Van der Auwera I, Wera S, Dewachter I, Van Leuven F. Van Dooren T, et al. Among authors: wera s. Am J Pathol. 2006 Jan;168(1):245-60. doi: 10.2353/ajpath.2006.050752. Am J Pathol. 2006. PMID: 16400027 Free PMC article.
42 results