Gorelick FS - Search Results

1

Phospholipase D1 corrects impaired betaAPP trafficking and neurite outgrowth in familial Alzheimer's disease-linked presenilin-1 mutant neurons.

Cai D, Zhong M, Wang R, Netzer WJ, Shields D, Zheng H, Sisodia SS, Foster DA, Gorelick FS, Xu H, Greengard P. Cai D, et al. Among authors: gorelick fs. Proc Natl Acad Sci U S A. 2006 Feb 7;103(6):1936-40. doi: 10.1073/pnas.0510710103. Epub 2006 Jan 31. Proc Natl Acad Sci U S A. 2006. PMID: 16449385 Free PMC article.

2

Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.

He G, Luo W, Li P, Remmers C, Netzer WJ, Hendrick J, Bettayeb K, Flajolet M, Gorelick F, Wennogle LP, Greengard P. He G, et al. Nature. 2010 Sep 2;467(7311):95-8. doi: 10.1038/nature09325. Nature. 2010. PMID: 20811458 Free PMC article.

3

Presenilin-1 uses phospholipase D1 as a negative regulator of beta-amyloid formation.

Cai D, Netzer WJ, Zhong M, Lin Y, Du G, Frohman M, Foster DA, Sisodia SS, Xu H, Gorelick FS, Greengard P. Cai D, et al. Among authors: gorelick fs. Proc Natl Acad Sci U S A. 2006 Feb 7;103(6):1941-6. doi: 10.1073/pnas.0510708103. Epub 2006 Jan 31. Proc Natl Acad Sci U S A. 2006. PMID: 16449386 Free PMC article.

4

Bidirectional regulation of Aβ levels by Presenilin 1.

Bustos V, Pulina MV, Kelahmetoglu Y, Sinha SC, Gorelick FS, Flajolet M, Greengard P. Bustos V, et al. Among authors: gorelick fs. Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):7142-7147. doi: 10.1073/pnas.1705235114. Epub 2017 May 22. Proc Natl Acad Sci U S A. 2017. PMID: 28533411 Free PMC article.

5

Phosphorylated Presenilin 1 decreases β-amyloid by facilitating autophagosome-lysosome fusion.

Bustos V, Pulina MV, Bispo A, Lam A, Flajolet M, Gorelick FS, Greengard P. Bustos V, et al. Among authors: gorelick fs. Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):7148-7153. doi: 10.1073/pnas.1705240114. Epub 2017 May 22. Proc Natl Acad Sci U S A. 2017. PMID: 28533369 Free PMC article.

6

Translocation of synapsin I in response to depolarization of isolated nerve terminals.

Sihra TS, Wang JK, Gorelick FS, Greengard P. Sihra TS, et al. Among authors: gorelick fs. Proc Natl Acad Sci U S A. 1989 Oct;86(20):8108-12. doi: 10.1073/pnas.86.20.8108. Proc Natl Acad Sci U S A. 1989. PMID: 2510160 Free PMC article.

7

Ca2+/calmodulin-dependent protein kinase II: identification of threonine-286 as the autophosphorylation site in the alpha subunit associated with the generation of Ca2+-independent activity.

Thiel G, Czernik AJ, Gorelick F, Nairn AC, Greengard P. Thiel G, et al. Proc Natl Acad Sci U S A. 1988 Sep;85(17):6337-41. doi: 10.1073/pnas.85.17.6337. Proc Natl Acad Sci U S A. 1988. PMID: 2842767 Free PMC article.

8

Improving the quality of immunoblots by chromatography of polyclonal antisera on keratin affinity columns.

Girault JA, Gorelick FS, Greengard P. Girault JA, et al. Among authors: gorelick fs. Anal Biochem. 1989 Oct;182(1):193-6. doi: 10.1016/0003-2697(89)90741-0. Anal Biochem. 1989. PMID: 2481415

9

Presence of calcium/calmodulin-dependent protein kinase II in nerve terminals of rat brain.

Walaas SI, Gorelick FS, Greengard P. Walaas SI, et al. Among authors: gorelick fs. Synapse. 1989;3(4):356-62. doi: 10.1002/syn.890030409. Synapse. 1989. PMID: 2545012

10

Ca2+/calmodulin-dependent protein kinase II: identification of autophosphorylation sites responsible for generation of Ca2+/calmodulin-independence.

Lai Y, Nairn AC, Gorelick F, Greengard P. Lai Y, et al. Proc Natl Acad Sci U S A. 1987 Aug;84(16):5710-4. doi: 10.1073/pnas.84.16.5710. Proc Natl Acad Sci U S A. 1987. PMID: 3475699 Free PMC article.

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