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Identification of hydroxywarfarin binding site in human UDP glucuronosyltransferase 1a10: phenylalanine90 is crucial for the glucuronidation of 6- and 7-hydroxywarfarin but not 8-hydroxywarfarin.
Miller GP, Lichti CF, Zielinska AK, Mazur A, Bratton SM, Gallus-Zawada A, Finel M, Moran JH, Radominska-Pandya A. Miller GP, et al. Among authors: finel m. Drug Metab Dispos. 2008 Nov;36(11):2211-8. doi: 10.1124/dmd.108.022863. Epub 2008 Aug 25. Drug Metab Dispos. 2008. PMID: 18725508 Free PMC article.
A potential role for human UDP-glucuronosyltransferase 1A4 promoter single nucleotide polymorphisms in the pharmacogenomics of tamoxifen and its derivatives.
Greer AK, Dates CR, Starlard-Davenport A, Edavana VK, Bratton SM, Dhakal IB, Finel M, Kadlubar SA, Radominska-Pandya A. Greer AK, et al. Among authors: finel m. Drug Metab Dispos. 2014 Sep;42(9):1392-400. doi: 10.1124/dmd.114.058016. Epub 2014 Jun 10. Drug Metab Dispos. 2014. PMID: 24917585 Free PMC article.
154 results