Purohit A - Search Results

1

17Beta-hydroxysteroid dehydrogenase Type 1 and Type 2: association between mRNA expression and activity in cell lines.

Day JM, Tutill HJ, Newman SP, Purohit A, Lawrence HR, Vicker N, Potter BV, Reed MJ. Day JM, et al. Among authors: purohit a. Mol Cell Endocrinol. 2006 Mar 27;248(1-2):246-9. doi: 10.1016/j.mce.2006.01.011. Epub 2006 Feb 21. Mol Cell Endocrinol. 2006. PMID: 16490301

2

The role of cytokines in regulating estrogen synthesis: implications for the etiology of breast cancer.

Purohit A, Newman SP, Reed MJ. Purohit A, et al. Breast Cancer Res. 2002;4(2):65-9. doi: 10.1186/bcr425. Epub 2002 Jan 14. Breast Cancer Res. 2002. PMID: 11879566 Free PMC article. Review.

3

Benzothiazole derivatives as novel inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1.

Su X, Vicker N, Ganeshapillai D, Smith A, Purohit A, Reed MJ, Potter BV. Su X, et al. Among authors: purohit a. Mol Cell Endocrinol. 2006 Mar 27;248(1-2):214-7. doi: 10.1016/j.mce.2005.10.022. Epub 2005 Dec 1. Mol Cell Endocrinol. 2006. PMID: 16325333

4

Novel, potent inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.

Allan GM, Bubert C, Vicker N, Smith A, Tutill HJ, Purohit A, Reed MJ, Potter BV. Allan GM, et al. Among authors: purohit a. Mol Cell Endocrinol. 2006 Mar 27;248(1-2):204-7. doi: 10.1016/j.mce.2005.10.021. Epub 2005 Dec 7. Mol Cell Endocrinol. 2006. PMID: 16337736

5

The role of 17beta-hydroxysteroid dehydrogenases in modulating the activity of 2-methoxyestradiol in breast cancer cells.

Newman SP, Ireson CR, Tutill HJ, Day JM, Parsons MF, Leese MP, Potter BV, Reed MJ, Purohit A. Newman SP, et al. Among authors: purohit a. Cancer Res. 2006 Jan 1;66(1):324-30. doi: 10.1158/0008-5472.CAN-05-2391. Cancer Res. 2006. PMID: 16397246

6

Modification of estrone at the 6, 16, and 17 positions: novel potent inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.

Allan GM, Lawrence HR, Cornet J, Bubert C, Fischer DS, Vicker N, Smith A, Tutill HJ, Purohit A, Day JM, Mahon MF, Reed MJ, Potter BV. Allan GM, et al. Among authors: purohit a. J Med Chem. 2006 Feb 23;49(4):1325-45. doi: 10.1021/jm050830t. J Med Chem. 2006. PMID: 16480268

7

Focused libraries of 16-substituted estrone derivatives and modified e-ring steroids: inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.

Vicker N, Lawrence HR, Allan GM, Bubert C, Smith A, Tutill HJ, Purohit A, Day JM, Mahon MF, Reed MJ, Potter BV. Vicker N, et al. Among authors: purohit a. ChemMedChem. 2006 Apr;1(4):464-81. doi: 10.1002/cmdc.200500087. ChemMedChem. 2006. PMID: 16892382

8

Effects of mutations and glycosylations on STS activity: a site-directed mutagenesis study.

Stengel C, Newman SP, Day JM, Tutill HJ, Reed MJ, Purohit A. Stengel C, et al. Among authors: purohit a. Mol Cell Endocrinol. 2008 Feb 13;283(1-2):76-82. doi: 10.1016/j.mce.2007.11.012. Epub 2007 Nov 22. Mol Cell Endocrinol. 2008. PMID: 18180093

9

17beta-hydroxysteroid dehydrogenase Type 1, and not Type 12, is a target for endocrine therapy of hormone-dependent breast cancer.

Day JM, Foster PA, Tutill HJ, Parsons MF, Newman SP, Chander SK, Allan GM, Lawrence HR, Vicker N, Potter BV, Reed MJ, Purohit A. Day JM, et al. Among authors: purohit a. Int J Cancer. 2008 May 1;122(9):1931-40. doi: 10.1002/ijc.23350. Int J Cancer. 2008. PMID: 18183589

10

Novel inhibitors of 17beta-hydroxysteroid dehydrogenase type 1: templates for design.

Allan GM, Vicker N, Lawrence HR, Tutill HJ, Day JM, Huchet M, Ferrandis E, Reed MJ, Purohit A, Potter BV. Allan GM, et al. Among authors: purohit a. Bioorg Med Chem. 2008 Apr 15;16(8):4438-56. doi: 10.1016/j.bmc.2008.02.059. Epub 2008 Mar 7. Bioorg Med Chem. 2008. PMID: 18329273

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