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Hsp60 and Hsp10 increase in colon mucosa of Crohn’s disease and ulcerative colitis.
Rodolico V, Tomasello G, Zerilli M, Martorana A, Pitruzzella A, Gammazza AM, David S, Zummo G, Damiani P, Accomando S, Conway de Macario E, Macario AJ, Cappello F. Rodolico V, et al. Cell Stress Chaperones. 2010 Nov;15(6):877-84. doi: 10.1007/s12192-010-0196-8. Cell Stress Chaperones. 2010. PMID: 20390473 Free PMC article.
Changes in immunohistochemical levels and subcellular localization after therapy and correlation and colocalization with CD68 suggest a pathogenetic role of Hsp60 in ulcerative colitis.
Tomasello G, Rodolico V, Zerilli M, Martorana A, Bucchieri F, Pitruzzella A, Marino Gammazza A, David S, Rappa F, Zummo G, Damiani P, Accomando S, Rizzo M, de Macario EC, Macario AJ, Cappello F. Tomasello G, et al. Among authors: rodolico v. Appl Immunohistochem Mol Morphol. 2011 Dec;19(6):552-61. doi: 10.1097/PAI.0b013e3182118e5f. Appl Immunohistochem Mol Morphol. 2011. PMID: 21441812 Clinical Trial.
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