Van Voorhis WC - Search Results

1

Structure of the conserved hypothetical protein MAL13P1.257 from Plasmodium falciparum.

Holmes MA, Buckner FS, Van Voorhis WC, Mehlin C, Boni E, Earnest TN, DeTitta G, Luft J, Lauricella A, Anderson L, Kalyuzhniy O, Zucker F, Schoenfeld LW, Hol WG, Merritt EA. Holmes MA, et al. Among authors: van voorhis wc. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Mar 1;62(Pt 3):180-5. doi: 10.1107/S1744309106005847. Epub 2006 Feb 24. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006. PMID: 16511296 Free PMC article.

2

Trypanosoma cruzi: use of herpes simplex virus-thymidine kinase as a negative selectable marker.

Buckner FS, Wilson AJ, Van Voorhis WC. Buckner FS, et al. Among authors: van voorhis wc. Exp Parasitol. 1997 Jul;86(3):171-80. doi: 10.1006/expr.1997.4163. Exp Parasitol. 1997. PMID: 9225767

3

Detection of live Trypanosoma cruzi in tissues of infected mice by using histochemical stain for beta-galactosidase.

Buckner FS, Wilson AJ, Van Voorhis WC. Buckner FS, et al. Among authors: van voorhis wc. Infect Immun. 1999 Jan;67(1):403-9. doi: 10.1128/IAI.67.1.403-409.1999. Infect Immun. 1999. PMID: 9864242 Free PMC article.

4

Adenosine analogues as inhibitors of Trypanosoma brucei phosphoglycerate kinase: elucidation of a novel binding mode for a 2-amino-N(6)-substituted adenosine.

Bressi JC, Choe J, Hough MT, Buckner FS, Van Voorhis WC, Verlinde CL, Hol WG, Gelb MH. Bressi JC, et al. Among authors: van voorhis wc. J Med Chem. 2000 Nov 2;43(22):4135-50. doi: 10.1021/jm000287a. J Med Chem. 2000. PMID: 11063610

5

Potent anti-Trypanosoma cruzi activities of oxidosqualene cyclase inhibitors.

Buckner FS, Griffin JH, Wilson AJ, Van Voorhis WC. Buckner FS, et al. Among authors: van voorhis wc. Antimicrob Agents Chemother. 2001 Apr;45(4):1210-5. doi: 10.1128/AAC.45.4.1210-1215.2001. Antimicrob Agents Chemother. 2001. PMID: 11257036 Free PMC article.

6

Cloning, heterologous expression, and substrate specificities of protein farnesyltransferases from Trypanosoma cruzi and Leishmania major.

Buckner FS, Eastman RT, Nepomuceno-Silva JL, Speelmon EC, Myler PJ, Van Voorhis WC, Yokoyama K. Buckner FS, et al. Among authors: van voorhis wc. Mol Biochem Parasitol. 2002 Jul;122(2):181-8. doi: 10.1016/s0166-6851(02)00099-3. Mol Biochem Parasitol. 2002. PMID: 12106872

7

Trypanosoma brucei prenylated-protein carboxyl methyltransferase prefers farnesylated substrates.

Buckner FS, Kateete DP, Lubega GW, Van Voorhis WC, Yokoyama K. Buckner FS, et al. Among authors: van voorhis wc. Biochem J. 2002 Nov 1;367(Pt 3):809-16. doi: 10.1042/BJ20020277. Biochem J. 2002. PMID: 12141948 Free PMC article.

8

Protein farnesyl and N-myristoyl transferases: piggy-back medicinal chemistry targets for the development of antitrypanosomatid and antimalarial therapeutics.

Gelb MH, Van Voorhis WC, Buckner FS, Yokoyama K, Eastman R, Carpenter EP, Panethymitaki C, Brown KA, Smith DF. Gelb MH, et al. Among authors: van voorhis wc. Mol Biochem Parasitol. 2003 Feb;126(2):155-63. doi: 10.1016/s0166-6851(02)00282-7. Mol Biochem Parasitol. 2003. PMID: 12615314 Review.

9

In vitro and in vivo antimalarial activity of peptidomimetic protein farnesyltransferase inhibitors with improved membrane permeability.

Carrico D, Ohkanda J, Kendrick H, Yokoyama K, Blaskovich MA, Bucher CJ, Buckner FS, Van Voorhis WC, Chakrabarti D, Croft SL, Gelb MH, Sebti SM, Hamilton AD. Carrico D, et al. Among authors: van voorhis wc. Bioorg Med Chem. 2004 Dec 15;12(24):6517-26. doi: 10.1016/j.bmc.2004.09.020. Bioorg Med Chem. 2004. PMID: 15556768

10

Protein farnesyl transferase inhibitors for the treatment of malaria and African trypanosomiasis.

Buckner FS, Eastman RT, Yokoyama K, Gelb MH, Van Voorhis WC. Buckner FS, et al. Among authors: van voorhis wc. Curr Opin Investig Drugs. 2005 Aug;6(8):791-7. Curr Opin Investig Drugs. 2005. PMID: 16121685 Review.

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