Ploegh HL - Search Results

1

Crystal structure of the boronic acid-based proteasome inhibitor bortezomib in complex with the yeast 20S proteasome.

Groll M, Berkers CR, Ploegh HL, Ovaa H. Groll M, et al. Among authors: ploegh hl. Structure. 2006 Mar;14(3):451-6. doi: 10.1016/j.str.2005.11.019. Structure. 2006. PMID: 16531229 Free article.

2

Chemistry-based functional proteomics reveals novel members of the deubiquitinating enzyme family.

Borodovsky A, Ovaa H, Kolli N, Gan-Erdene T, Wilkinson KD, Ploegh HL, Kessler BM. Borodovsky A, et al. Among authors: ploegh hl. Chem Biol. 2002 Oct;9(10):1149-59. doi: 10.1016/s1074-5521(02)00248-x. Chem Biol. 2002. PMID: 12401499

3

Chemistry in living cells: detection of active proteasomes by a two-step labeling strategy.

Ovaa H, van Swieten PF, Kessler BM, Leeuwenburgh MA, Fiebiger E, van den Nieuwendijk AM, Galardy PJ, van der Marel GA, Ploegh HL, Overkleeft HS. Ovaa H, et al. Among authors: ploegh hl. Angew Chem Int Ed Engl. 2003 Aug 11;42(31):3626-9. doi: 10.1002/anie.200351314. Angew Chem Int Ed Engl. 2003. PMID: 12916032 No abstract available.

4

Zinc-finger protein A20, a regulator of inflammation and cell survival, has de-ubiquitinating activity.

Evans PC, Ovaa H, Hamon M, Kilshaw PJ, Hamm S, Bauer S, Ploegh HL, Smith TS. Evans PC, et al. Among authors: ploegh hl. Biochem J. 2004 Mar 15;378(Pt 3):727-34. doi: 10.1042/BJ20031377. Biochem J. 2004. PMID: 14748687 Free PMC article.

5

Activity-based ubiquitin-specific protease (USP) profiling of virus-infected and malignant human cells.

Ovaa H, Kessler BM, Rolén U, Galardy PJ, Ploegh HL, Masucci MG. Ovaa H, et al. Among authors: ploegh hl. Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2253-8. doi: 10.1073/pnas.0308411100. Proc Natl Acad Sci U S A. 2004. PMID: 14982996 Free PMC article.

6

Chemistry-based functional proteomics: mechanism-based activity-profiling tools for ubiquitin and ubiquitin-like specific proteases.

Hemelaar J, Galardy PJ, Borodovsky A, Kessler BM, Ploegh HL, Ovaa H. Hemelaar J, et al. Among authors: ploegh hl. J Proteome Res. 2004 Mar-Apr;3(2):268-76. doi: 10.1021/pr0341080. J Proteome Res. 2004. PMID: 15113103 Review.

7

Structure of the ubiquitin hydrolase UCH-L3 complexed with a suicide substrate.

Misaghi S, Galardy PJ, Meester WJ, Ovaa H, Ploegh HL, Gaudet R. Misaghi S, et al. Among authors: ploegh hl. J Biol Chem. 2005 Jan 14;280(2):1512-20. doi: 10.1074/jbc.M410770200. Epub 2004 Nov 5. J Biol Chem. 2005. PMID: 15531586 Free article.

8

Small-molecule inhibitors and probes for ubiquitin- and ubiquitin-like-specific proteases.

Borodovsky A, Ovaa H, Meester WJ, Venanzi ES, Bogyo MS, Hekking BG, Ploegh HL, Kessler BM, Overkleeft HS. Borodovsky A, et al. Among authors: ploegh hl. Chembiochem. 2005 Feb;6(2):287-91. doi: 10.1002/cbic.200400236. Chembiochem. 2005. PMID: 15651044 No abstract available.

9

Activity probe for in vivo profiling of the specificity of proteasome inhibitor bortezomib.

Berkers CR, Verdoes M, Lichtman E, Fiebiger E, Kessler BM, Anderson KC, Ploegh HL, Ovaa H, Galardy PJ. Berkers CR, et al. Among authors: ploegh hl. Nat Methods. 2005 May;2(5):357-62. doi: 10.1038/nmeth759. Epub 2005 Apr 21. Nat Methods. 2005. PMID: 15846363

10

Phosphoproteomic analysis with a solid-phase capture-release-tag approach.

Tseng HC, Ovaa H, Wei NJ, Ploegh H, Tsai LH. Tseng HC, et al. Chem Biol. 2005 Jul;12(7):769-77. doi: 10.1016/j.chembiol.2005.05.012. Chem Biol. 2005. PMID: 16039524

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