Lovejoy DB - Search Results

1

PCTH: a novel orally active chelator for the treatment of iron overload disease.

Lovejoy DB, Kalinowski D, Bernhardt PV, Richardson DR. Lovejoy DB, et al. Hemoglobin. 2006;30(1):93-104. doi: 10.1080/03630260500455367. Hemoglobin. 2006. PMID: 16540421 Review.

2

Novel "hybrid" iron chelators derived from aroylhydrazones and thiosemicarbazones demonstrate selective antiproliferative activity against tumor cells.

Lovejoy DB, Richardson DR. Lovejoy DB, et al. Blood. 2002 Jul 15;100(2):666-76. doi: 10.1182/blood.v100.2.666. Blood. 2002. PMID: 12091363 Free article.

3

Novel di-2-pyridyl-derived iron chelators with marked and selective antitumor activity: in vitro and in vivo assessment.

Yuan J, Lovejoy DB, Richardson DR. Yuan J, et al. Among authors: lovejoy db. Blood. 2004 Sep 1;104(5):1450-8. doi: 10.1182/blood-2004-03-0868. Epub 2004 May 18. Blood. 2004. PMID: 15150082 Free article.

4

Dipyridyl thiosemicarbazone chelators with potent and selective antitumor activity form iron complexes with redox activity.

Richardson DR, Sharpe PC, Lovejoy DB, Senaratne D, Kalinowski DS, Islam M, Bernhardt PV. Richardson DR, et al. Among authors: lovejoy db. J Med Chem. 2006 Nov 2;49(22):6510-21. doi: 10.1021/jm0606342. J Med Chem. 2006. PMID: 17064069

5

Chelators at the cancer coalface: desferrioxamine to Triapine and beyond.

Yu Y, Wong J, Lovejoy DB, Kalinowski DS, Richardson DR. Yu Y, et al. Among authors: lovejoy db. Clin Cancer Res. 2006 Dec 1;12(23):6876-83. doi: 10.1158/1078-0432.CCR-06-1954. Clin Cancer Res. 2006. PMID: 17145804 Review.

6

Design, synthesis, and characterization of novel iron chelators: structure-activity relationships of the 2-benzoylpyridine thiosemicarbazone series and their 3-nitrobenzoyl analogues as potent antitumor agents.

Kalinowski DS, Yu Y, Sharpe PC, Islam M, Liao YT, Lovejoy DB, Kumar N, Bernhardt PV, Richardson DR. Kalinowski DS, et al. Among authors: lovejoy db. J Med Chem. 2007 Jul 26;50(15):3716-29. doi: 10.1021/jm070445z. Epub 2007 Jun 30. J Med Chem. 2007. PMID: 17602603

7

2-Acetylpyridine thiosemicarbazones are potent iron chelators and antiproliferative agents: redox activity, iron complexation and characterization of their antitumor activity.

Richardson DR, Kalinowski DS, Richardson V, Sharpe PC, Lovejoy DB, Islam M, Bernhardt PV. Richardson DR, et al. Among authors: lovejoy db. J Med Chem. 2009 Mar 12;52(5):1459-70. doi: 10.1021/jm801585u. J Med Chem. 2009. PMID: 19216562

8

The medicinal chemistry of novel iron chelators for the treatment of cancer.

Kovacevic Z, Kalinowski DS, Lovejoy DB, Yu Y, Suryo Rahmanto Y, Sharpe PC, Bernhardt PV, Richardson DR. Kovacevic Z, et al. Among authors: lovejoy db. Curr Top Med Chem. 2011;11(5):483-99. doi: 10.2174/156802611794785190. Curr Top Med Chem. 2011. PMID: 21192781 Review.

9

The iron chelator, deferasirox, as a novel strategy for cancer treatment: oral activity against human lung tumor xenografts and molecular mechanism of action.

Lui GY, Obeidy P, Ford SJ, Tselepis C, Sharp DM, Jansson PJ, Kalinowski DS, Kovacevic Z, Lovejoy DB, Richardson DR. Lui GY, et al. Among authors: lovejoy db. Mol Pharmacol. 2013 Jan;83(1):179-90. doi: 10.1124/mol.112.081893. Epub 2012 Oct 16. Mol Pharmacol. 2013. PMID: 23074173

10

Iron chelators as anti-neoplastic agents: current developments and promise of the PIH class of chelators.

Lovejoy DB, Richardson DR. Lovejoy DB, et al. Curr Med Chem. 2003 Jun;10(12):1035-49. doi: 10.2174/0929867033457557. Curr Med Chem. 2003. PMID: 12678675 Review.

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